Job Description A2A4P0 Confidence 100.00% Date Wed Jul 10 14:06:11 BST 2013 Rank 8 Aligned Residues 381 % Identity 15% Template c2vbcA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:dengue 4 ns3 full-length protein; PDBTitle: crystal structure of the ns3 protease-helicase from dengue2 virus Resolution 3.15 Å Model Dimensions (Å) X:68.631 Y:74.172 Z:50.023

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		602	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	H	D	N	Q	I	L	I	V	I	G	E	T	G	S	G	K	T	T	Q	I	T	Q	Y	L	A	E	A	G	Y	T	S	R	G	K	I	G	C	T	Q	P	R	R	V	A	A	M	S	V	A	K	R	V	S	E	E	F	G	C	C
Query Conservation
Alig confidence																																																								.	.	.	.	.	.
Template Conservation																																																								.	.	.	.	.	.
Template Sequence		F	R	K	K	R	L	T	I	M	D	L	H	P	G	A	G	K	T	K	R	I	L	P	S	I	V	R	E	A	L	K	R	R	L	R	T	L	I	L	A	P	T	R	V	V	A	A	E	M	E	E	A	L	R	.	.	.	.	.	.
Template Known Secondary structure			S	T	T									T	T	T			T	T	T												T	T								S	S											T	T	.	.	.	.	.	.
Template Predicted Secondary structure																																																								.	.	.	.	.	.
Template SS confidence
		183	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
		662	.	.	.	.	.	.	.	670	.		.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Predicted Secondary structure												.
Query SS confidence												.
Query Sequence		L	G	Q	E	V	G	Y	T	I	R	.	F	E	D	C	T	S	P	E	T	V	I	K	Y	M	T	D	G	M	L	L	R	E	C	L	I	D	P	D	L	T	Q	Y	A	I	I	M	L	D	E	A	H	E	R	T	I	H	T	D	V
Query Conservation												.
Alig confidence		.										.
Template Conservation		.
Template Sequence		.	G	L	P	I	R	Y	Q	T	P	A	V	K	S	D	H	T	G	R	E	I	V	D	L	M	C	H	A	T	F	T	T	R	L	L	S	S	T	R	V	P	N	Y	N	L	I	V	M	D	E	A	H	F	T	D	P	C	S	V	A
Template Known Secondary structure		.	T	S							T	T		S						S	S																		S						S						S	T	T			S
Template Predicted Secondary structure		.
Template SS confidence
			237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.
		721	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780
Predicted Secondary structure
Query SS confidence
Query Sequence		L	F	G	L	L	K	K	T	V	Q	K	R	Q	D	M	K	L	I	V	T	S	A	T	L	D	A	V	K	F	S	Q	Y	F	Y	E	A	P	I	F	T	I	P	G	R	T	Y	P	V	E	I	L	Y	T	K	E	P	E	T	D	Y
Query Conservation
Alig confidence												.														.	.	.	.	.	.	.	.	.	.
Template Conservation												.														.	.	.	.	.	.	.	.	.	.
Template Sequence		A	R	G	Y	I	S	T	R	V	E	.	M	G	E	A	A	A	I	F	M	T	A	T	P	.	.	.	.	.	.	.	.	.	.	P	G	S	T	D	P	F	P	Q	S	N	S	P	I	E	D	I	E	R	E	I	P	E	R	S	W
Template Known Secondary structure												.		T	S								S	S		.	.	.	.	.	.	.	.	.	.	T	T				S	S				S	S											S	S
Template Predicted Secondary structure												.														.	.	.	.	.	.	.	.	.	.
Template SS confidence
		296	.	.	.	300	.	.	.	.	.		.	.	.	.	310	.	.	.	.	.	.	.	.											.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.
		781	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Predicted Secondary structure
Query SS confidence
Query Sequence		L	D	A	S	L	I	T	V	M	Q	I	H	L	T	E	P	P	G	D	I	L	V	F	L	T	G	Q	E	E	I	D	T	A	C	E	I	L	Y	E	R	M	K	S	L	G	P	D	V	P	E	L	I	I	L	P	V	Y	S	A	L
Query Conservation
Alig confidence							.	.	.	.	.	.																														.	.	.	.	.	.	.	.	.
Template Conservation							.	.	.	.	.	.																														.	.	.	.	.	.	.	.	.
Template Sequence		N	T	G	F	D	.	.	.	.	.	.	W	I	T	D	Y	Q	G	K	T	V	W	F	V	P	S	I	K	A	G	N	D	I	A	N	C	L	R	K	S	.	.	.	.	.	.	.	.	.	G	K	R	V	I	Q	L	S	R	K	T
Template Known Secondary structure			S	S			.	.	.	.	.	.							S							S	S													T	T	.	.	.	.	.	.	.	.	.	T								T	T	T
Template Predicted Secondary structure							.	.	.	.	.	.																														.	.	.	.	.	.	.	.	.
Template SS confidence
		345	.	.	.	.							350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.										.	380	.	.	.	.	.	.	.	.	.
		841	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.			.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.
Predicted Secondary structure																																												.	.
Query SS confidence																																												.	.
Query Sequence		P	S	E	M	Q	T	R	I	F	D	P	A	P	P	G	S	R	K	V	V	I	A	T	N	I	A	E	T	S	L	T	I	D	G	I	Y	Y	V	V	D	P	G	.	.	F	V	K	Q	K	V	Y	N	S	K	T	G	I	D	Q	L
Query Conservation																																												.	.
Alig confidence		.	.	.	.																														.									.	.
Template Conservation		.	.	.	.																														.
Template Sequence		.	.	.	.	F	D	T	E	Y	P	K	T	K	L	T	D	W	D	F	V	V	T	T	D	I	S	E	M	G	A	N	F	R	.	A	G	R	V	I	D	P	R	R	C	L	K	P	V	I	L	T	D	G	P	E	R	V	I	L	A
Template Known Secondary structure		.	.	.	.					T						S			S						G	G	G	G	T	T					.		S																S	S	S
Template Predicted Secondary structure		.	.	.	.																														.
Template SS confidence
						390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.		.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.
		899	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.		.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.
Predicted Secondary structure																										.
Query SS confidence																										.
Query Sequence		V	V	T	P	I	S	Q	A	Q	A	K	Q	R	A	G	R	A	G	R	T	G	P	G	K	.	C	Y	R	L	Y	T	E	R	A	Y	R	D	E	M	L	T	T	N	V	P	E	I	Q	R	T	N	L	A	S	T	V	L	S	L	K
Query Conservation																										.
Alig confidence																										.							.	.	.	.	.	.
Template Conservation																																	.	.	.	.	.	.
Template Sequence		G	P	I	P	V	T	P	A	S	A	A	Q	R	R	G	R	I	G	R	N	P	A	Q	E	D	D	Q	Y	V	F	S	.	.	.	.	.	.	G	D	P	L	K	N	D	E	D	H	A	H	W	T	E	A	K	M	L	L	D	N	I
Template Known Secondary structure																	T	S	S		S			S	S								.	.	.	.	.	.	S							T	T	B											T	T	S
Template Predicted Secondary structure																																	.	.	.	.	.	.
Template SS confidence
		445	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.							.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.
		958	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.						980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.
Predicted Secondary structure																								.	.	.	.	.
Query SS confidence																								.	.	.	.	.
Query Sequence		A	M	G	I	N	D	L	L	S	F	D	F	M	D	A	P	P	M	E	T	L	I	.	.	.	.	.	T	A	M	E	Q	L	Y	T	L	G	A	L	D	D	E	G	L	L	T	R	L	G	R	R	M	A	E	F	P	L	E	P	M
Query Conservation																								.	.	.	.	.
Alig confidence																								.	.	.	.	.
Template Conservation
Template Sequence		Y	T	P	E	G	I	I	P	T	L	F	G	P	E	R	E	K	T	Q	A	I	D	G	E	F	R	L	R	G	E	Q	R	K	T	F	V	E	L	M	R	R	G	D	L	P	V	W	L	S	Y	K	V	A	S	A	G	I	S	Y	K
Template Known Secondary structure				T	T								G	G	G	G	G	G			S		T	T	T	T				T	T											T	S												T	T	T			S	S
Template Predicted Secondary structure
Template SS confidence
		499	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.
		1013	.	.	.	.	.	.	1020	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	C	K	M	L	I	M	S	V	H	L	G	C	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	R	E	W	C	F	T	G	E	R	N	N	Q	I
Template Known Secondary structure				T	T	T	T				G	G	G
Template Predicted Secondary structure
Template SS confidence
		559	560	.	.	.	.	.	.	.	.	.	570	.	.