Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 298 Aligned Residues 244 % Identity 18% Template c3zonA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: human tyk2 pseudokinase domain bound to a kinase inhibitor Resolution 2.15 Å

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		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40		.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.
Predicted Secondary structure																																						.
Query SS confidence																																						.
Query Sequence		H	A	Q	Y	E	M	L	E	T	I	G	Q	G	G	C	A	Q	V	K	L	A	Q	H	R	L	T	G	T	H	V	A	V	K	V	I	V	.	K	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T	D	H	P	N
Query Conservation																																						.
Alig confidence																										.												.
Template Conservation																										.
Template Sequence		Q	K	E	I	T	Q	L	S	H	L	G	Q	G	T	R	T	N	V	Y	E	G	R	L	R	.	V	E	L	R	V	V	L	K	V	L	D	P	S	H	H	D	I	A	L	A	F	Y	E	T	A	S	L	M	S	Q	V	S	H	T	H
Template Known Secondary structure		G	G	G											T	T										.												S																	T	T				T	T
Template Predicted Secondary structure																										.
Template SS confidence
		586	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.		610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.
		64	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.		.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.
Predicted Secondary structure																																				.
Query SS confidence																																				.
Query Sequence		I	I	S	L	L	Q	V	I	E	T	K	K	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	Q	N	A	G	.	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L	S	A	V	N	Y	C	H	N	Q	G
Query Conservation																																				.
Alig confidence																																				.
Template Conservation
Template Sequence		L	A	F	V	H	G	V	C	V	R	G	P	E	N	I	M	V	T	E	Y	V	E	H	G	P	L	D	V	W	L	R	R	E	R	G	H	V	P	M	A	W	K	M	V	V	A	Q	Q	L	A	S	A	L	S	Y	L	E	N	K	N
Template Known Secondary structure		B										T	T										T	T		B								T	T	T																								T	T
Template Predicted Secondary structure
Template SS confidence
		670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.
		123	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		I	V	H	R	D	L	T	P	D	N	I	M	V	E	K	D	G	K	V	K	I	I	D	F	G	L	G	T	Q	E	K	P	A	Q	K	L	N	L	F	C	E	N	Y	P	F	S	T	P	E	V	L	L	S	R	P	Y	D	M	R	K
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	V	H	G	N	V	C	G	R	N	I	L	L	A	R	L	G	L	A	E	G	T	S	P	F	I	K	L	S	D	P	G	V	G	L	G	A	L	S	R	E	E	R	V	E	R	I	P	W	L	A	P	E	C	L	P	L	S	T	A
Template Known Secondary structure								S	G	G	G									S	T	T												S		G	G	G	S								T	T	T	T	S		G	G	G					T	T
Template Predicted Secondary structure
Template SS confidence
		730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.
		183	.	.	.	.	.	.	190	.	.	.	.	.	.	.		.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.
Predicted Secondary structure																	.
Query SS confidence																	.
Query Sequence		I	D	V	W	G	L	G	V	V	L	Y	F	M	V	T	.	G	K	I	L	F	D	A	A	S	I	E	K	L	R	K	Q	I	V	A	G	K	C	S	V	P	C	R	L	S	V	E	L	Q	D	L	I	R	L	L	M	T	D	N	P
Query Conservation																	.
Alig confidence																	.																									.	.	.	.
Template Conservation																																										.	.	.	.
Template Sequence		M	D	K	W	G	F	G	A	T	L	L	E	I	C	F	D	G	E	A	P	L	Q	S	R	S	P	S	E	K	E	H	F	Y	Q	R	Q	H	R	L	P	.	.	.	.	E	P	Q	L	A	T	L	T	S	Q	C	L	T	Y	E	P
Template Known Secondary structure																T	T	T			T	T	T	T	S											T	T					.	.	.	.												T		S	S	G
Template Predicted Secondary structure																																										.	.	.	.
Template SS confidence
		795	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.					.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850
		242	.	.	.	.	.	.	.	250	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	L	R	P	T	V	A	E	V	M	V	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	Q	R	P	S	F	R	T	I	L	R	D
Template Known Secondary structure		G	G	S
Template Predicted Secondary structure
Template SS confidence
		854	.	.	.	.	.	860	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D