Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 240 Aligned Residues 247 % Identity 21% Template c3zbfA_ PDB info PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase ros; PDBTitle: structure of human ros1 kinase domain in complex with crizotinib Resolution 2.20 Å

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		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.				.	30	.	.	.	.	.	.	.	.	.	40			.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																										.	.	.													.	.
Query SS confidence																										.	.	.													.	.
Query Sequence		H	A	Q	Y	E	M	L	E	T	I	G	Q	G	G	C	A	Q	V	K	L	A	Q	H	R	.	.	.	L	T	G	T	H	V	A	V	K	V	I	V	.	.	K	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T
Query Conservation																										.	.	.													.	.
Alig confidence																										.	.	.													.	.
Template Conservation
Template Sequence		R	E	K	L	T	L	R	L	L	L	G	S	G	E	V	Y	E	G	T	A	V	D	I	L	G	V	G	S	G	E	I	K	V	A	V	K	T	L	K	K	G	S	T	D	Q	E	K	I	E	F	L	K	E	A	H	L	M	S	K	F
Template Known Secondary structure		G	G	G																			T	S	S		S	S													S	S																		T
Template Predicted Secondary structure
Template SS confidence
		1942	.	.	.	.	.	.	.	1950	.	.	.	.	.	.	.	.	.	1960	.	.	.	.	.	.	.	.	.	1970	.	.	.	.	.	.	.	.	.	1980	.	.	.	.	.	.	.	.	.	1990	.	.	.	.	.	.	.	.	.	2000	.
		60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.								.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.
Predicted Secondary structure																																					.	.	.	.	.	.	.
Query SS confidence																																					.	.	.	.	.	.	.
Query Sequence		D	H	P	N	I	I	S	L	L	Q	V	I	E	T	K	K	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	Q	.	.	.	.	.	.	.	N	A	G	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L
Query Conservation																																					.	.	.	.	.	.	.
Alig confidence																																					.	.	.	.	.	.	.
Template Conservation
Template Sequence		N	H	P	N	I	L	K	Q	L	G	V	C	L	L	N	E	P	Q	Y	I	I	L	E	L	M	E	G	G	D	L	L	T	Y	L	R	K	A	R	M	A	T	F	Y	G	P	L	L	T	L	V	D	L	V	D	L	C	V	D	I	S
Template Known Secondary structure				T	T	B									S	S	S	S									T	T		B											S		T	T			S	S
Template Predicted Secondary structure
Template SS confidence
		2005	.	.	.	.	2010	.	.	.	.	.	.	.	.	.	2020	.	.	.	.	.	.	.	.	.	2030	.	.	.	.	.	.	.	.	.	2040	.	.	.	.	.	.	.	.	.	2050	.	.	.	.	.	.	.	.	.	2060	.	.	.	.
		113	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	A	V	N	Y	C	H	N	Q	G	I	V	H	R	D	L	T	P	D	N	I	M	V	E	K	D	G	K	V	K	I	I	D	F	G	L	G	T	Q	E	K	P	A	Q	K	L	N	L	F	C	E	N	Y	P	F	S	T	P	E	V
Query Conservation
Alig confidence																																									.	.	.	.
Template Conservation																																									.	.	.	.
Template Sequence		K	G	C	V	Y	L	E	R	M	H	F	I	H	R	D	L	A	A	R	N	C	L	V	S	V	K	D	Y	T	S	P	R	I	V	K	I	G	D	F	.	.	.	.	G	L	A	R	D	I	Y	L	P	V	R	W	M	A	P	E	S
Template Known Secondary structure										T	T				S				G	G	G				S		S	S	S	S	S										.	.	.	.	T	T								G	G	G	S
Template Predicted Secondary structure																																									.	.	.	.
Template SS confidence
		2065	.	.	.	.	2070	.	.	.	.	.	.	.	.	.	2080	.	.	.	.	.	.	.	.	.	2090	.	.	.	.	.	.	.	.	.	2100	.	.	.					.	.	.	.	.	.	2110	.	.	.	.	.	.	.	.	.	2120
		173	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.		.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.		.	.	220	.	.	.	.	.	.	.	.	.	230
Predicted Secondary structure																											.																					.
Query SS confidence																											.																					.
Query Sequence		L	L	S	R	P	Y	D	M	R	K	I	D	V	W	G	L	G	V	V	L	Y	F	M	V	T	.	G	K	I	L	F	D	A	A	S	I	E	K	L	R	K	Q	I	V	A	G	.	K	C	S	V	P	C	R	L	S	V	E	L	Q
Query Conservation																											.																					.
Alig confidence								.																			.																					.
Template Conservation								.
Template Sequence		L	M	D	G	I	F	.	T	T	Q	S	D	V	W	S	F	G	I	L	I	W	E	I	L	T	L	G	H	Q	P	Y	P	A	H	S	N	L	D	V	L	N	Y	V	Q	T	G	G	R	L	E	P	P	R	N	C	P	D	D	L	W
Template Known Secondary structure								.																		T	T	S			S	S	T	T												T	T							T	T
Template Predicted Secondary structure								.
Template SS confidence
		2133	.	.	.	.	.		.	2140	.	.	.	.	.	.	.	.	.	2150	.	.	.	.	.	.	.	.	.	2160	.	.	.	.	.	.	.	.	.	2170	.	.	.	.	.	.	.	.	.	2180	.	.	.	.	.	.	.	.	.	2190	.
		231	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	L	I	R	L	L	M	T	D	N	P	E	L	R	P	T	V	A	E	V	M	V	H	P	W	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		N	L	M	T	Q	C	W	A	Q	E	P	D	Q	R	P	T	F	H	R	I	Q	D	Q	L	Q	L
Template Known Secondary structure								T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		2192	.	.	.	.	.	.	.	2200	.	.	.	.	.	.	.	.	.	2210	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D