Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 73 Aligned Residues 238 % Identity 25% Template c3vw6B_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor Resolution 2.40 Å

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		6	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	Q	Y	E	M	L	E	T	I	G	Q	G	G	C	A	Q	V	K	L	A	Q	H	R	L	T	G	T	H	V	A	V	K	V	I	V	K	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T	D	H	P	N	I	I
Query Conservation
Alig confidence																																						.	.	.	.	.
Template Conservation																																						.	.	.	.	.
Template Sequence		D	E	N	G	D	R	V	V	L	G	K	G	T	Y	G	I	V	Y	A	G	R	D	L	S	N	Q	V	R	I	A	I	K	E	I	P	E	.	.	.	.	.	Q	P	L	H	E	E	I	A	L	H	K	H	L	K	H	K	N	I	V
Template Known Secondary structure			T	T	S	S	B							S	S	S								T	T	T												.	.	.	.	.											T	T				T	T	B
Template Predicted Secondary structure																																						.	.	.	.	.
Template SS confidence
		678	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.						.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.
		66	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.				.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.
Predicted Secondary structure																																		.	.	.
Query SS confidence																																		.	.	.
Query Sequence		S	L	L	Q	V	I	E	T	K	K	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	Q	N	A	G	.	.	.	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L	S	A	V	N	Y	C	H	N	Q	G
Query Conservation																																		.	.	.
Alig confidence																																		.	.	.
Template Conservation
Template Sequence		Q	Y	L	G	S	F	S	E	N	G	F	I	K	I	F	M	E	Q	V	P	G	G	S	L	S	A	L	L	R	S	K	W	G	P	L	K	D	N	E	Q	T	I	G	F	Y	T	K	Q	I	L	E	G	L	K	Y	L	H	D	N	Q
Template Known Secondary structure										T	T										T	T		B								T	T				T	T																						T	T
Template Predicted Secondary structure
Template SS confidence
		739	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.
		123	.	.	.	.	.	.	130	.	.	.	.	.		.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.		.	180
Predicted Secondary structure															.																																												.
Query SS confidence															.																																												.
Query Sequence		I	V	H	R	D	L	T	P	D	N	I	M	V	.	E	K	D	G	K	V	K	I	I	D	F	G	L	G	T	Q	E	K	P	A	Q	K	L	N	L	F	C	E	N	Y	P	F	S	T	P	E	V	L	L	S	R	P	Y	.	D	M
Query Conservation															.																																												.
Alig confidence															.																.	.	.	.	.	.	.	.	.																				.
Template Conservation																															.	.	.	.	.	.	.	.	.
Template Sequence		I	V	H	R	D	I	K	G	D	N	V	L	I	N	T	Y	S	G	V	L	K	I	S	D	F	G	T	S	K	.	.	.	.	.	.	.	.	.	R	L	T	G	T	L	Q	Y	M	A	P	E	I	I	D	K	G	P	R	G	Y	G
Template Known Secondary structure					S			S	G	G	G					T	T	T									S	S			.	.	.	.	.	.	.	.	.						G	G	G										G	G	G		S
Template Predicted Secondary structure																															.	.	.	.	.	.	.	.	.
Template SS confidence
		799	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.										.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.
		181	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.				.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.
Predicted Secondary structure																																	.	.	.
Query SS confidence																																	.	.	.
Query Sequence		R	K	I	D	V	W	G	L	G	V	V	L	Y	F	M	V	T	G	K	I	L	F	D	A	A	S	I	E	K	L	R	.	.	.	K	Q	I	V	A	G	K	C	S	V	P	C	R	L	S	V	E	L	Q	D	L	I	R	L	L	M
Query Conservation																																	.	.	.
Alig confidence																																	.	.	.
Template Conservation
Template Sequence		K	A	A	D	I	W	S	L	G	C	T	I	I	E	M	A	T	G	K	P	P	F	Y	E	L	G	E	P	Q	A	A	M	F	K	V	G	M	F	K	V	H	P	E	I	P	E	S	M	S	A	E	A	K	A	F	I	L	K	C	F
Template Known Secondary structure																			S	S		T	T	G	G	G		S												T							T	T	S												T
Template Predicted Secondary structure
Template SS confidence
		860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.
		238	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	D	N	P	E	L	R	P	T	V	A	E	V	M	V	H	P	W	V	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	P	D	P	D	K	R	A	C	A	N	D	L	L	V	D	E	F	L	K
Template Known Secondary structure			S		T	T	T	S								T	S	G	G	G
Template Predicted Secondary structure
Template SS confidence
		920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D