Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 207 Aligned Residues 242 % Identity 24% Template c3v5qB_ PDB info PDB header:transferase/transferase inhibitor Chain: B: PDB Molecule:nt-3 growth factor receptor; PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models Resolution 2.20 Å

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		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.		20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40		.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.
Predicted Secondary structure																	.																						.
Query SS confidence																	.																						.
Query Sequence		H	A	Q	Y	E	M	L	E	T	I	G	Q	G	G	C	.	A	Q	V	K	L	A	Q	H	R	L	T	G	T	H	V	A	V	K	V	I	V	.	K	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T	D	H	P
Query Conservation																	.																						.
Alig confidence																	.																						.
Template Conservation
Template Sequence		R	R	D	I	V	L	K	R	E	L	G	F	K	V	F	L	A	E	C	Y	N	L	S	P	T	K	D	K	M	L	V	A	V	K	A	L	K	D	P	T	L	A	A	R	K	D	F	Q	R	E	A	E	L	L	T	N	L	Q	H	E
Template Known Secondary structure		G	G	G																		S			S	S	S	S											S																						T
Template Predicted Secondary structure
Template SS confidence
		535	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.
		63	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.		.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.
Predicted Secondary structure																																					.
Query SS confidence																																					.
Query Sequence		N	I	I	S	L	L	Q	V	I	E	T	K	K	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	Q	N	A	G	.	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L	S	A	V	N	Y	C	H	N	Q
Query Conservation																																					.
Alig confidence														.	.																						.
Template Conservation														.	.
Template Sequence		H	I	V	K	F	Y	G	V	C	G	D	P	.	.	L	I	M	V	F	E	Y	M	K	H	G	D	L	N	K	F	L	R	A	H	G	P	E	L	G	L	S	Q	M	L	H	I	A	S	Q	I	A	S	G	M	V	Y	L	A	S	Q
Template Known Secondary structure		T	B											.	.									T	T									T	T																										T
Template Predicted Secondary structure														.	.
Template SS confidence
		599	600	.	.	.	.	.	.	.	.	.	610			.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.
		122	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	I	V	H	R	D	L	T	P	D	N	I	M	V	E	K	D	G	K	V	K	I	I	D	F	G	L	G	T	Q	E	K	P	A	Q	K	L	N	L	F	C	E	N	Y	P	F	S	T	P	E	V	L	L	S	R	P	Y	D	M	R
Query Conservation
Alig confidence																																								.	.	.																	.
Template Conservation																																								.	.	.																	.
Template Sequence		H	F	V	H	R	D	L	A	T	R	N	C	L	V	G	A	N	L	L	V	K	I	G	D	F	G	M	D	V	Y	S	T	D	Y	Y	R	T	M	.	.	.	L	P	I	R	W	M	P	P	E	S	I	M	Y	R	K	F	.	T	T
Template Known Secondary structure		T				S			S	G	G	G					G	G	G												S	G	G	G		B				.	.	.	B		G	G	G												.
Template Predicted Secondary structure																																								.	.	.																	.
Template SS confidence
		674	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.				.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.		.	.
		182	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.		.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.		.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																		.																					.
Query SS confidence																		.																					.
Query Sequence		K	I	D	V	W	G	L	G	V	V	L	Y	F	M	V	T	.	G	K	I	L	F	D	A	A	S	I	E	K	L	R	K	Q	I	V	A	G	.	K	C	S	V	P	C	R	L	S	V	E	L	Q	D	L	I	R	L	L	M	T	D
Query Conservation																		.																					.
Alig confidence																		.																					.
Template Conservation
Template Sequence		E	S	D	V	W	S	F	G	V	I	L	W	E	I	F	T	Y	G	K	Q	P	W	F	Q	L	S	N	T	E	V	I	E	C	I	T	Q	G	R	V	L	E	R	P	R	V	C	P	K	E	V	Y	D	V	M	L	G	C	W	Q	R
Template Known Secondary structure																T	T	T	S			T	T	T	T	S												T							T	T															S
Template Predicted Secondary structure
Template SS confidence
		750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.
		240	.	.	.	.	.	.	.	.	.	250	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	P	E	L	R	P	T	V	A	E	V	M	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		E	P	Q	Q	R	L	N	I	K	E	I	Y	K
Template Known Secondary structure		S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		810	.	.	.	.	.	.	.	.	.	820	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D