Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 257 Aligned Residues 248 % Identity 25% Template c3mtfB_ PDB info PDB header:transferase Chain: B: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the acvr1 kinase in complex with a 2-2 aminopyridine inhibitor Resolution 2.15 Å

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	K	F	H	A	Q	Y	E	M	L	E	T	I	G	Q	G	G	C	A	Q	V	K	L	A	Q	H	R	L	T	G	T	H	V	A	V	K	V	I	V	K	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T	D	H
Query Conservation
Alig confidence																												.	.
Template Conservation																												.	.
Template Sequence		R	T	V	A	R	D	I	T	L	L	E	C	V	G	K	G	R	Y	G	E	V	W	R	G	S	W	.	.	Q	G	E	N	V	A	V	K	I	F	S	S	R	D	E	K	S	W	F	R	E	T	E	L	Y	N	T	V	M	L	R	H
Template Known Secondary structure				T	T	T	T											T	T									.	.	T	T										G	G	G														S
Template Predicted Secondary structure																												.	.
Template SS confidence
		202	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.			.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.
		62	.	.	.	.	.	.	.	70	.	.	.					.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.
Predicted Secondary structure														.	.	.	.
Query SS confidence														.	.	.	.
Query Sequence		P	N	I	I	S	L	L	Q	V	I	E	T	.	.	.	.	K	K	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	Q	N	A	G	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L	S	A	V	N	Y
Query Conservation														.	.	.	.
Alig confidence														.	.	.	.																						.
Template Conservation																																							.
Template Sequence		E	N	I	L	G	F	I	A	S	D	M	T	S	R	H	S	S	T	Q	L	W	L	I	T	H	Y	H	E	M	G	S	L	Y	D	Y	L	Q	.	L	T	T	L	D	T	V	S	C	L	R	I	V	L	S	I	A	S	G	L	A	H
Template Known Secondary structure		T	T	B												T	T												T	T		B							.				B
Template Predicted Secondary structure																																							.
Template SS confidence
		260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.		.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.
		118	.	120	.	.	.									.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.						.	.	.	.	.	.	.	.	160	.	.	.	.
Predicted Secondary structure								.	.	.	.	.	.	.	.																													.	.	.	.	.
Query SS confidence								.	.	.	.	.	.	.	.																													.	.	.	.	.
Query Sequence		C	H	N	Q	G	I	.	.	.	.	.	.	.	.	V	H	R	D	L	T	P	D	N	I	M	V	E	K	D	G	K	V	K	I	I	D	F	G	L	G	T	Q	.	.	.	.	.	E	K	P	A	Q	K	L	N	L	F	C	E	N
Query Conservation								.	.	.	.	.	.	.	.																													.	.	.	.	.
Alig confidence								.	.	.	.	.	.	.	.																													.	.	.	.	.
Template Conservation
Template Sequence		L	H	I	E	I	F	G	T	Q	G	K	P	A	I	A	H	R	D	L	K	S	K	N	I	L	V	K	K	N	G	Q	C	C	I	A	D	L	G	L	A	V	M	H	S	Q	S	T	N	Q	L	D	V	G	N	N	P	R	V	G	T
Template Known Secondary structure				S		B		S	T	T		B						S			S	G	G	G					T	T	S								T	T						T	T	T	T
Template Predicted Secondary structure
Template SS confidence
		319	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.
		165	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.						.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.
Predicted Secondary structure																			.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																			.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.
Query Sequence		Y	P	F	S	T	P	E	V	L	L	S	R	P	Y	D	M	R	.	.	.	.	.	K	I	D	V	W	G	L	G	V	V	L	Y	F	M	V	T	G	K	I	L	F	D	A	A	S	I	E	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																			.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.
Alig confidence																			.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		K	R	Y	M	A	P	E	V	L	D	E	T	I	Q	V	D	C	F	D	S	Y	K	R	V	D	I	W	A	F	G	L	V	L	W	E	V	A	R	R	M	V	S	N	G	I	V	E	D	Y	K	P	P	F	Y	D	V	V	P	N	D
Template Known Secondary structure		G	G	G							T	T				T	T																						T	T	B		B	T	T	B							T	T	T	T	T	S		S	S
Template Predicted Secondary structure
Template SS confidence
		379	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.
					209	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.									.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.
Predicted Secondary structure		.	.	.																	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.																	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	K	L	R	K	Q	I	V	A	G	K	C	S	V	P	C	R	.	.	.	.	.	.	.	.	L	S	V	E	L	Q	D	L	I	R	L	L	M	T	D	N	P	E	L	R	P	T	V	A	E	V	M	V
Query Conservation		.	.	.																	.	.	.	.	.	.	.	.
Alig confidence		.	.	.																	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		P	S	F	E	D	M	R	K	V	V	C	V	D	Q	Q	R	P	N	I	P	N	R	W	F	S	D	P	T	L	T	S	L	A	K	L	M	K	E	C	W	Y	Q	N	P	S	A	R	L	T	A	L	R	I	K	K
Template Known Secondary structure												T	T	S								G	G	G	G	G	S																S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		439	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D