Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 203 Aligned Residues 245 % Identity 24% Template c3lxnA_ PDB info PDB header:transferase Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.50 Å

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		6	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.					.	30	.	.	.	.	.	.	.	.	.	40			.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																									.	.	.	.													.	.
Query SS confidence																									.	.	.	.													.	.
Query Sequence		A	Q	Y	E	M	L	E	T	I	G	Q	G	G	C	A	Q	V	K	L	A	Q	H	R	.	.	.	.	L	T	G	T	H	V	A	V	K	V	I	V	.	.	K	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T
Query Conservation																									.	.	.	.													.	.
Alig confidence																									.	.	.	.													.	.
Template Conservation
Template Sequence		R	Y	L	K	K	I	R	D	L	G	E	G	H	F	G	K	V	S	L	Y	C	Y	D	P	T	N	D	G	T	G	E	M	V	A	V	K	A	L	K	A	D	A	G	P	Q	H	R	S	G	W	K	Q	E	I	D	I	L	R	T	L
Template Known Secondary structure		G	G											S	S										T	T	S	S	S												S	S
Template Predicted Secondary structure
Template SS confidence
		895	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.
		60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.			.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.
Predicted Secondary structure																		.	.
Query SS confidence																		.	.
Query Sequence		D	H	P	N	I	I	S	L	L	Q	V	I	E	T	K	K	.	.	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	Q	N	A	G	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L	S	A	V	N	Y
Query Conservation																		.	.
Alig confidence																		.	.																				.
Template Conservation																																							.
Template Sequence		Y	H	E	H	I	I	K	Y	K	G	C	C	E	D	A	G	A	A	S	L	Q	L	V	M	E	Y	V	P	L	G	S	L	R	D	Y	L	P	.	R	H	S	I	G	L	A	Q	L	L	L	F	A	Q	Q	I	C	E	G	M	A	Y
Template Known Secondary structure				T	T	B										T	T	T	T										T	T		B					G	G	.	G	S
Template Predicted Secondary structure																																							.
Template SS confidence
		955	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.		.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.
		118	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		C	H	N	Q	G	I	V	H	R	D	L	T	P	D	N	I	M	V	E	K	D	G	K	V	K	I	I	D	F	G	L	G	T	Q	E	K	P	A	Q	K	L	N	L	F	C	E	N	Y	P	F	S	T	P	E	V	L	L	S	R	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		L	H	A	Q	H	Y	I	H	R	D	L	A	A	R	N	V	L	L	D	N	D	R	L	V	K	I	G	D	F	G	L	A	K	A	V	P	E	G	H	E	Y	R	V	G	D	S	P	V	F	W	Y	A	P	E	C	L	K	E	Y	K
Template Known Secondary structure					T	T				S			S	G	G	G						T	T								T	T						T	T				B						G	G	G								S		B
Template Predicted Secondary structure
Template SS confidence
		1014	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.
		178	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.																.	.	.	.	.	.	210	.	.	.	.	.	.	.		.	.	220	.
Predicted Secondary structure																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.															.
Query SS confidence																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.															.
Query Sequence		Y	D	M	R	K	I	D	V	W	G	L	G	V	V	L	Y	F	M	V	T	G	K	I	L	F	D	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	A	S	I	E	K	L	R	K	Q	I	V	A	G	.	K	C	S	V
Query Conservation																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.															.
Alig confidence			.																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.															.
Template Conservation			.
Template Sequence		F	.	Y	Y	A	S	D	V	W	S	F	G	V	T	L	Y	E	L	L	T	H	C	D	S	S	Q	S	P	P	T	K	F	L	E	L	I	G	I	A	Q	G	Q	M	T	V	L	R	L	T	E	L	L	E	R	G	E	R	L	P	R
Template Known Secondary structure			.																		T	T	T		G	G	G	S											S	T	T	G	G	G											T	T
Template Predicted Secondary structure			.
Template SS confidence
		1078		.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.
		222	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	C	R	L	S	V	E	L	Q	D	L	I	R	L	L	M	T	D	N	P	E	L	R	P	T	V	A	E	V	M	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	D	K	C	P	A	E	V	Y	H	L	M	K	N	C	W	E	T	E	A	S	F	R	P	T	F	E	N	L	I	P
Template Known Secondary structure			T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1137	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D