Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 139 Aligned Residues 248 % Identity 25% Template c3lxkA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase jak3; PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6 Resolution 2.00 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.					.	30	.	.	.	.	.	.	.	.	.	40		.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																										.	.	.	.													.
Query SS confidence																										.	.	.	.													.
Query Sequence		H	A	Q	Y	E	M	L	E	T	I	G	Q	G	G	C	A	Q	V	K	L	A	Q	H	R	.	.	.	.	L	T	G	T	H	V	A	V	K	V	I	V	.	K	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T
Query Conservation																										.	.	.	.													.
Alig confidence																										.	.	.	.													.
Template Conservation
Template Sequence		E	R	H	L	K	Y	I	S	Q	L	G	K	G	N	F	G	S	V	E	L	C	R	Y	D	P	L	G	D	N	T	G	A	L	V	A	V	K	Q	L	Q	H	S	G	P	D	Q	Q	R	D	F	Q	R	E	I	Q	I	L	K	A	L
Template Known Secondary structure		G	G	G											T	T										T	T	S	S	S		S									S	S																		T
Template Predicted Secondary structure
Template SS confidence
		819	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.
		60	.	.	.	.	.	.	.	.	.	70	.	.	.			.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.		.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.
Predicted Secondary structure																.	.																									.
Query SS confidence																.	.																									.
Query Sequence		D	H	P	N	I	I	S	L	L	Q	V	I	E	T	.	.	K	K	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	Q	N	A	G	.	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L	S	A	V	N
Query Conservation																.	.																									.
Alig confidence																.	.																									.
Template Conservation
Template Sequence		H	S	D	F	I	V	K	Y	R	G	V	S	Y	G	P	G	R	Q	S	L	R	L	V	M	E	Y	L	P	S	G	C	L	R	D	F	L	Q	R	H	R	A	R	L	D	A	S	R	L	L	L	Y	S	S	Q	I	C	K	G	M	E
Template Known Secondary structure				T	T	B									S	S	S	S											T	T		B									G	G	G
Template Predicted Secondary structure
Template SS confidence
		879	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.
		117	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.					.	.	.	.	.	.	.	.	170	.	.
Predicted Secondary structure																																															.	.	.	.
Query SS confidence																																															.	.	.	.
Query Sequence		Y	C	H	N	Q	G	I	V	H	R	D	L	T	P	D	N	I	M	V	E	K	D	G	K	V	K	I	I	D	F	G	L	G	T	Q	E	K	P	A	Q	K	L	N	L	F	.	.	.	.	C	E	N	Y	P	F	S	T	P	E	V
Query Conservation																																															.	.	.	.
Alig confidence																																															.	.	.	.
Template Conservation
Template Sequence		Y	L	G	S	R	R	C	V	H	R	D	L	A	A	R	N	I	L	V	E	S	E	A	H	V	K	I	A	D	F	G	L	A	K	L	L	P	L	D	K	D	Y	Y	V	V	R	E	P	G	Q	S	P	I	F	W	Y	A	P	E	S
Template Known Secondary structure						T	T				S			S	G	G	G						T	T								T	T						T	T		S					S	S				S		G	G	G
Template Predicted Secondary structure
Template SS confidence
		939	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.
		173	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.											.	.	.	.	.	210	.	.	.	.	.	.	.		.	.	220	.
Predicted Secondary structure																																		.	.	.	.	.	.	.	.	.	.														.
Query SS confidence																																		.	.	.	.	.	.	.	.	.	.														.
Query Sequence		L	L	S	R	P	Y	D	M	R	K	I	D	V	W	G	L	G	V	V	L	Y	F	M	V	T	G	K	I	L	F	D	A	.	.	.	.	.	.	.	.	.	.	A	S	I	E	K	L	R	K	Q	I	V	A	G	.	K	C	S	V
Query Conservation																																		.	.	.	.	.	.	.	.	.	.														.
Alig confidence								.																										.	.	.	.	.	.	.	.	.	.														.
Template Conservation								.
Template Sequence		L	S	D	N	I	F	.	S	R	Q	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	Y	C	D	K	S	C	S	P	S	A	E	F	L	R	M	M	V	P	A	L	S	R	L	L	E	L	L	E	E	G	Q	R	L	P	A
Template Known Secondary structure								.																		T	T	T		G	G	G	S																						T	T
Template Predicted Secondary structure								.
Template SS confidence
		999	1000	.	.	.	.		.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.
		222	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	C	R	L	S	V	E	L	Q	D	L	I	R	L	L	M	T	D	N	P	E	L	R	P	T	V	A	E	V	M	V	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	P	A	C	P	A	E	V	H	E	L	M	K	L	C	W	A	P	S	P	Q	D	R	P	S	F	S	A	L	G	P	Q
Template Known Secondary structure			T	T													T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1063	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D