Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 112 Aligned Residues 251 % Identity 25% Template c3kvwA_ PDB info PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand Resolution 2.28 Å

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	K	F	H	A	Q	Y	E	M	L	E	T	I	G	Q	G	G	C	A	Q	V	K	L	A	Q	H	R	L	T	G	T	H	V	A	V	K	V	I	V	K	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T	D	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	H	V	A	Y	R	Y	E	V	L	K	V	I	G	K	G	S	F	G	Q	V	V	K	A	Y	D	H	K	V	H	Q	H	V	A	L	K	M	V	R	N	E	K	R	F	H	R	Q	A	A	E	E	I	R	I	L	E	H	L	R	K
Template Known Secondary structure					T	T	T										S	S	S									T	T	T	T										S																				T
Template Predicted Secondary structure
Template SS confidence
		143	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.
								62	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.			.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.
Predicted Secondary structure		.	.	.	.	.	.																																				.	.
Query SS confidence		.	.	.	.	.	.																																				.	.
Query Sequence		.	.	.	.	.	.	P	N	I	I	S	L	L	Q	V	I	E	T	K	K	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	Q	N	A	.	.	G	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L	S
Query Conservation		.	.	.	.	.	.																																				.	.
Alig confidence		.	.	.	.	.	.																								.												.	.
Template Conservation																															.
Template Sequence		Q	D	K	D	N	T	M	N	V	I	H	M	L	E	N	F	T	F	R	N	H	I	C	M	T	F	E	L	L	.	S	M	N	L	Y	E	L	I	K	K	N	K	F	Q	G	F	S	L	P	L	V	R	K	F	A	H	S	I	L	Q
Template Known Secondary structure		T		T	T	S		S		B										T	T										.			B								T	T	T
Template Predicted Secondary structure																															.
Template SS confidence
		203	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.		.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.
		114	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.			140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.
Predicted Secondary structure																												.	.
Query SS confidence																												.	.
Query Sequence		A	V	N	Y	C	H	N	Q	G	I	V	H	R	D	L	T	P	D	N	I	M	V	E	K	D	G	.	.	K	V	K	I	I	D	F	G	L	G	T	Q	E	K	P	A	Q	K	L	N	L	F	C	E	N	Y	P	F	S	T	P	E
Query Conservation																												.	.
Alig confidence																												.	.																					.	.	.
Template Conservation																																																		.	.	.
Template Sequence		C	L	D	A	L	H	K	N	R	I	I	H	C	D	L	K	P	E	N	I	L	L	K	Q	Q	G	R	S	G	I	K	V	I	D	F	G	S	S	C	Y	E	H	Q	R	V	Y	T	I	.	.	.	Q	S	R	F	Y	R	A	P	E
Template Known Secondary structure										T				S			S	G	G	G				S	S	T	T	S									T	T				T	T							.	.	.			G	G	G
Template Predicted Secondary structure																																																		.	.	.
Template SS confidence
		262	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.				310	.	.	.	.	.	.	.	.
		172	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.
Predicted Secondary structure																																																					.	.	.	.	.	.	.	.	.
Query SS confidence																																																					.	.	.	.	.	.	.	.	.
Query Sequence		V	L	L	S	R	P	Y	D	M	R	K	I	D	V	W	G	L	G	V	V	L	Y	F	M	V	T	G	K	I	L	F	D	A	A	S	I	E	K	L	R	K	Q	I	V	A	G	K	C	S	V	P	.	.	.	.	.	.	.	.	.
Query Conservation																																																					.	.	.	.	.	.	.	.	.
Alig confidence									.																																												.	.	.	.	.	.	.	.	.
Template Conservation									.
Template Sequence		V	I	L	G	A	R	Y	.	G	M	P	I	D	M	W	S	L	G	C	I	L	A	E	L	L	T	G	Y	P	L	L	P	G	E	D	E	G	D	Q	L	A	C	M	I	E	L	L	G	M	P	S	Q	K	L	L	D	A	S	K	R
Template Known Secondary structure					T	B			.		T																	S	S		S	S			S	S																						T	B	T	T
Template Predicted Secondary structure									.
Template SS confidence
		320	.	.	.	.	.	.		.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.
																																																	223	.	.	.	.	.	.	230	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	C	R	L	S	V	E	L	Q	D	L	I	R	L
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		A	K	N	F	V	S	K	G	Y	P	R	Y	C	T	V	T	T	L	S	D	V	V	L	N	G	G	R	S	R	R	G	K	L	R	G	P	P	E	S	R	E	W	G	N	A	L	K	G	C	D	D	P	L	F	L	D	F	L	K	Q
Template Known Secondary structure						B					B	T	T	S																T	T						S	T	T		S						T	T	T
Template Predicted Secondary structure
Template SS confidence
		379	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.
		236	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	M	T	D	N	P	E	L	R	P	T	V	A	E	V	M	V	H	P	W	V	T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		C	L	E	W	D	P	A	V	R	M	T	P	G	Q	A	L	R	H	P	W	L	R
Template Known Secondary structure			T		S	S	T	T	T	S								T	S	T	T	T
Template Predicted Secondary structure
Template SS confidence
		442	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D