Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 246 Aligned Residues 225 % Identity 24% Template c3k54A_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase btk; PDBTitle: structures of human bruton's tyrosine kinase in active and inactive2 conformations suggests a mechanism of activation for tec family3 kinases. Resolution 1.94 Å

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		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	A	Q	Y	E	M	L	E	T	I	G	Q	G	G	C	A	Q	V	K	L	A	Q	H	R	L	T	G	T	H	V	A	V	K	V	I	V	K	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T	D	H	P	N	I
Query Conservation
Alig confidence																										.											.	.	.	.	.	.	.
Template Conservation																										.											.	.	.	.	.	.	.
Template Sequence		P	K	D	L	T	F	L	K	E	L	G	T	G	Q	F	G	V	V	K	Y	G	K	W	R	.	G	Q	Y	D	V	A	I	K	M	I	.	.	.	.	.	.	.	K	E	F	I	E	E	A	K	V	M	M	N	L	S	H	E	K	L
Template Known Secondary structure		G	G	G									S	T	T	S	S								T	.	T	T									.	.	.	.	.	.	.				T	T											T	T	B
Template Predicted Secondary structure																										.											.	.	.	.	.	.	.
Template SS confidence
		399	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.		.	.	.	.	.	.	.	430	.	.								.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450
		65	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.		.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.
Predicted Secondary structure																															.
Query SS confidence																															.
Query Sequence		I	S	L	L	Q	V	I	E	T	K	K	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	.	Q	N	A	G	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L	S	A	V	N	Y	C	H	N	Q	G	I
Query Conservation																															.
Alig confidence																															.
Template Conservation
Template Sequence		V	Q	L	Y	G	V	C	T	K	Q	R	P	I	F	I	I	T	E	Y	M	A	N	G	C	L	L	N	Y	L	R	E	M	R	H	R	F	Q	T	Q	Q	L	L	E	M	C	K	D	V	C	E	A	M	E	Y	L	E	S	K	Q	F
Template Known Secondary structure										S	S	S	S									T	T										G	G	G																								T	T
Template Predicted Secondary structure
Template SS confidence
		458	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.
		124	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	H	R	D	L	T	P	D	N	I	M	V	E	K	D	G	K	V	K	I	I	D	F	G	L	G	T	Q	E	K	P	A	Q	K	L	N	L	F	C	E	N	Y	P	F	S	T	P	E	V	L	L	S	R	P	Y	D	M	R	K	I
Query Conservation
Alig confidence																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.
Template Conservation																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.
Template Sequence		L	H	R	D	L	A	A	R	N	C	L	V	N	D	Q	G	V	V	K	V	S	D	F	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	F	P	V	R	W	S	P	P	E	V	L	M	Y	S	K	F	.	S	S	K	S
Template Known Secondary structure				S			S	G	G	G					T	T										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.			G	G	G												.
Template Predicted Secondary structure																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.
Template SS confidence
		518	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.																.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.		.	.	560	.
		184	.	.	.	.	.	190	.	.	.	.	.	.	.		.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.		.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.
Predicted Secondary structure																.																					.
Query SS confidence																.																					.
Query Sequence		D	V	W	G	L	G	V	V	L	Y	F	M	V	T	.	G	K	I	L	F	D	A	A	S	I	E	K	L	R	K	Q	I	V	A	G	.	K	C	S	V	P	C	R	L	S	V	E	L	Q	D	L	I	R	L	L	M	T	D	N	P
Query Conservation																.																					.
Alig confidence																.																					.
Template Conservation
Template Sequence		D	I	W	A	F	G	V	L	M	W	E	I	Y	S	L	G	K	M	P	Y	E	R	F	T	N	S	E	T	A	E	H	I	A	Q	G	L	R	L	Y	R	P	H	L	A	S	E	K	V	Y	T	I	M	Y	S	C	W	H	E	K	A
Template Known Secondary structure															T	T	S			T	T	T	T	S											T	T							T	T	S											T	T		S	S	G
Template Predicted Secondary structure
Template SS confidence
		579	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.
		242	.	.	.	.	.	.	.	250	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	L	R	P	T	V	A	E	V	M	V	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	E	R	P	T	F	K	I	L	L	S	N
Template Known Secondary structure		G	G	S
Template Predicted Secondary structure
Template SS confidence
		639	640	.	.	.	.	.	.	.	.	.	650

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D