Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 219 Aligned Residues 246 % Identity 26% Template c3fupB_ PDB info PDB header:transferase Chain: B: PDB Molecule:tyrosine-protein kinase jak2; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 2.40 Å

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		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.					.	30	.	.	.	.	.	.	.	.	.	40		.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																										.	.	.	.													.
Query SS confidence																										.	.	.	.													.
Query Sequence		H	A	Q	Y	E	M	L	E	T	I	G	Q	G	G	C	A	Q	V	K	L	A	Q	H	R	.	.	.	.	L	T	G	T	H	V	A	V	K	V	I	V	.	K	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T
Query Conservation																										.	.	.	.													.
Alig confidence																										.	.	.	.													.
Template Conservation
Template Sequence		E	R	H	L	K	F	L	Q	Q	L	G	K	G	N	F	G	S	V	E	M	C	R	Y	D	P	L	Q	D	N	T	G	E	V	V	A	V	K	K	L	Q	H	S	T	E	E	H	L	R	D	F	E	R	E	I	E	I	L	K	S	L
Template Known Secondary structure		G	G	G											S	S										T	T	S	S	S											S																			T
Template Predicted Secondary structure
Template SS confidence
		846	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.
		60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.		.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.
Predicted Secondary structure																																								.
Query SS confidence																																								.
Query Sequence		D	H	P	N	I	I	S	L	L	Q	V	I	E	T	K	K	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	Q	N	A	G	.	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L	S	A	V	N	Y	C
Query Conservation																																								.
Alig confidence															.	.																								.
Template Conservation															.	.
Template Sequence		Q	H	D	N	I	V	K	Y	K	G	V	C	Y	.	.	S	N	L	K	L	I	M	E	Y	L	P	Y	G	S	L	R	D	Y	L	Q	K	H	K	E	R	I	D	H	I	K	L	L	Q	Y	T	S	Q	I	C	K	G	M	E	Y	L
Template Known Secondary structure				T	T	B									.	.											T	T		B					T	T	T	S	T	T	T
Template Predicted Secondary structure															.	.
Template SS confidence
		906	.	.	.	910	.	.	.	.	.	.	.	.			.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.
		119	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160			.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.
Predicted Secondary structure																																												.	.
Query SS confidence																																												.	.
Query Sequence		H	N	Q	G	I	V	H	R	D	L	T	P	D	N	I	M	V	E	K	D	G	K	V	K	I	I	D	F	G	L	G	T	Q	E	K	P	A	Q	K	L	N	L	.	.	F	C	E	N	Y	P	F	S	T	P	E	V	L	L	S	R
Query Conservation																																												.	.
Alig confidence																																												.	.
Template Conservation
Template Sequence		G	T	K	R	Y	I	H	R	D	L	A	T	R	N	I	L	V	E	N	E	N	R	V	K	I	G	D	F	G	L	T	K	V	L	P	Q	D	K	E	K	V	K	E	P	G	E	S	P	I	F	W	Y	A	P	E	S	L	T	E	S
Template Known Secondary structure			T	T	T								G	G	G						T	T								T	T						T	T							S	S				G	G	G
Template Predicted Secondary structure
Template SS confidence
		968	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.
		177	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.																	.	.	.	.	.	210	.	.	.	.	.	.	.		.	.
Predicted Secondary structure																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.
Query SS confidence																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.
Query Sequence		P	Y	D	M	R	K	I	D	V	W	G	L	G	V	V	L	Y	F	M	V	T	G	K	I	L	F	D	A	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	S	I	E	K	L	R	K	Q	I	V	A	G	.	K	C
Query Conservation																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.
Alig confidence				.																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.														.
Template Conservation				.
Template Sequence		K	F	.	S	V	A	S	D	V	W	S	F	G	V	V	L	Y	E	L	F	T	Y	I	E	K	S	K	S	P	P	A	E	F	M	R	M	I	G	N	D	K	Q	G	Q	M	I	V	F	H	L	I	E	L	L	K	N	N	G	R	L
Template Known Secondary structure				.																			T	T		G	G	G	S											S				S	S												T	T
Template Predicted Secondary structure				.
Template SS confidence
		1030	.		.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.
		220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	V	P	C	R	L	S	V	E	L	Q	D	L	I	R	L	L	M	T	D	N	P	E	L	R	P	T	V	A	E	V	M	V	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	R	P	D	G	C	P	D	E	I	Y	M	I	M	T	E	C	W	N	N	N	V	N	Q	R	P	S	F	R	D	L	A	L	R
Template Known Secondary structure					T	T			T	T									T		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1089	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D