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Job DescriptionA0JLX3
Confidence100.00%DateWed Jul 10 14:37:17 BST 2013
Rank166Aligned Residues243
% Identity22%Templatec3fmeA_
PDB info PDB header:transferaseChain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 6; PDBTitle: crystal structure of human mitogen-activated protein kinase kinase 62 (mek6) activated mutant (s207d, t211d)
Resolution2.26 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1........10.........20.........30.........40.........50.........60
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Query Sequence  MEKFHAQYEMLETIGQGGCAQVKLAQHRLTGTHVAVKVIVKRECWFNPVMSEAELLMMTD
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Template Sequence  MEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRNSQEQKRLLMDLDISMRTVD
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GGG
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TT

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   46...50.........60.........70.........80.........90.........100.....
 
   61........70.........80.........90.... .....100.........110.......
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Query Sequence  HPNIISLLQVIETKKKLYLIMELCEGKSLYQHIQ. . . NAGYLQEDEACPLFKQLLSAVNY
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Template Sequence  CPFTVTFYGALFREGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEH
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TTB


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   109110.........120.........130.........140.........150.........160........
 
   118. 120.........130.........140.........150.........160.........170......
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Query Sequence  CH. NQGIVHRDLTPDNIMVEKDGKVKIIDFGLGTQEKPAQKLNLFCENYPFSTPEVLLSR
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Template Sequence  LHSKLSVIHRDVKPSNVLINALGQVKMCDFA. . . . . . . . . . . . . . GCKPYMAPERINPEL
Template Known Secondary structure  S






SGGG

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B



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S
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   169170.........180.........190......... 200.........210....
 
   177..180.........190.........200...... ...210.........220... ......230...
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Query Sequence  PYDMRKIDVWGLGVVLYFMVTGKILFDAAS. . IEKLRKQIVAGKCSVPC. RLSVELQDLI
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Template Sequence  NQYSVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFT
Template Known Secondary structure  T


TS
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   230.........240.........250.........260.........270.........280.........
 
   234.....240.........250.......
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Query Sequence  RLLMTDNPELRPTVAEVMVHPWVT
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Template Sequence  SQCLKKNSKERPTYPELMQHPFFT
Template Known Secondary structure  T
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   292.......300.........310.....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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