Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 212 Aligned Residues 243 % Identity 25% Template c3eygA_ PDB info PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase; PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes Resolution 1.90 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.					.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Predicted Secondary structure																								.	.	.	.
Query SS confidence																								.	.	.	.
Query Sequence		H	A	Q	Y	E	M	L	E	T	I	G	Q	G	G	C	A	Q	V	K	L	A	Q	.	.	.	.	H	R	L	T	G	T	H	V	A	V	K	V	I	V	K	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T	D
Query Conservation																								.	.	.	.
Alig confidence																								.	.	.	.																				.	.	.
Template Conservation																																															.	.	.
Template Sequence		K	R	F	L	K	R	I	R	D	L	G	E	G	H	F	G	K	V	E	L	C	R	Y	D	P	E	G	D	N	T	G	E	Q	V	A	V	K	S	L	K	P	H	I	A	D	.	.	.	L	K	K	E	I	E	I	L	R	N	L	Y
Template Known Secondary structure		G	G	G											S	S										T	T	S	S	S		S															.	.	.										T
Template Predicted Secondary structure																																															.	.	.
Template SS confidence
		872	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.				.	.	.	920	.	.	.	.	.	.	.	.
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.		.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																							.
Query SS confidence																																							.
Query Sequence		H	P	N	I	I	S	L	L	Q	V	I	E	T	K	K	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	Q	N	A	G	.	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L	S	A	V	N	Y	C	H
Query Conservation																																							.
Alig confidence											.																												.
Template Conservation											.
Template Sequence		H	E	N	I	V	K	Y	K	G	.	I	C	T	E	N	G	I	K	L	I	M	E	F	L	P	S	G	S	L	K	E	Y	L	P	K	N	K	N	K	I	N	L	K	Q	Q	L	K	Y	A	V	Q	I	C	K	G	M	D	Y	L	G
Template Known Secondary structure			T	T	B						.															T	T		B					T	G	G	G	T	T	T
Template Predicted Secondary structure											.
Template SS confidence
		934	.	.	.	.	.	940	.	.		.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.
		120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160			.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.
Predicted Secondary structure																																											.	.
Query SS confidence																																											.	.
Query Sequence		N	Q	G	I	V	H	R	D	L	T	P	D	N	I	M	V	E	K	D	G	K	V	K	I	I	D	F	G	L	G	T	Q	E	K	P	A	Q	K	L	N	L	.	.	F	C	E	N	Y	P	F	S	T	P	E	V	L	L	S	R	P
Query Conservation																																											.	.
Alig confidence																																											.	.
Template Conservation
Template Sequence		S	R	Q	Y	V	H	R	D	L	A	A	R	N	V	L	V	E	S	E	H	Q	V	K	I	G	D	F	G	L	T	K	A	I	E	T	D	K	E	T	V	K	D	D	R	D	S	P	V	F	W	Y	A	P	E	C	L	M	Q	S	K
Template Known Secondary structure			T	T				S			S	G	G	G						T	T								T	T						T	T					S			T	T			G	G	G
Template Predicted Secondary structure
Template SS confidence
		996	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.
		178	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.																.	.	.	.	210	.	.	.	.	.	.	.		.	.	220	.
Predicted Secondary structure																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.
Query SS confidence																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.
Query Sequence		Y	D	M	R	K	I	D	V	W	G	L	G	V	V	L	Y	F	M	V	T	G	K	I	L	F	D	A	A	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	I	E	K	L	R	K	Q	I	V	A	G	.	K	C	S	V
Query Conservation																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.
Alig confidence			.																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													.
Template Conservation			.
Template Sequence		F	.	Y	I	A	S	D	V	W	S	F	G	V	T	L	H	E	L	L	T	Y	C	D	S	D	S	S	P	M	A	L	F	L	K	M	I	G	P	T	H	G	Q	M	T	V	T	R	L	V	N	T	L	K	E	G	K	R	L	P	C
Template Known Secondary structure			.																		T	T	T		G	G	G												S			G	G	G											T	T
Template Predicted Secondary structure			.
Template SS confidence
		1058		.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.
		222	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	C	R	L	S	V	E	L	Q	D	L	I	R	L	L	M	T	D	N	P	E	L	R	P	T	V	A	E	V	M	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	P	N	C	P	D	E	V	Y	Q	L	M	R	K	C	W	E	F	Q	P	S	N	R	T	S	F	Q	N	L	I	E
Template Known Secondary structure			T	T												T			S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1117	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D