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Job DescriptionA0JLX3
Confidence100.00%DateWed Jul 10 14:37:17 BST 2013
Rank194Aligned Residues241
% Identity26%Templatec3d4qA_
PDB info PDB header:transferaseChain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase; PDBTitle: pyrazole-based inhibitors of b-raf kinase
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40. ........50........
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Query Sequence  EKFHAQYEMLETIGQGGCAQVKLAQHRLTGTHVAVKVIVK. . . RECWFNPVMSEAELLMM
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Template Sequence  EIPDGQITVGQRIGSGSFGTVYKGKW. . . HGDVAVKMLNVTAPTPQQLQAFKNEVGVLRK
Template Known Secondary structure  B

TT

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   451........460.........470...... ...480.........490.........500.......
 
   5960.........70.........80.........90........ .100.........110.......
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Query Sequence  TDHPNIISLLQVIETKKKLYLIMELCEGKSLYQHIQNAGY. LQEDEACPLFKQLLSAVNY
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Template Sequence  TRHVNILLFMG. YSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDY
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   508.510........ .520.........530.........540.........550.........560......
 
   118.120.........130.........140.........150.........160.........170.......
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Query Sequence  CHNQGIVHRDLTPDNIMVEKDGKVKIIDFGLGTQEKPAQKLNLFCENYPFSTPEVLLSRP
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Template Sequence  LHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVLS. . . . . . . . . GSILWMAPEVIRMQD
Template Known Secondary structure  TT
B
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SGGGTTT


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   567..570.........580.........590.........600.. .......610.......
 
   178 .180.........190.........200.........210.........220 .........
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Query Sequence  Y. . DMRKIDVWGLGVVLYFMVTGKILFDAASIEKLRKQIVAGKCS. . . . . . VPCRLSVEL
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Template Sequence  KNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAM
Template Known Secondary structure  S


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   630.........640.........650.........660.........670.........680.........
 
   230.........240.........250.....
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Query Sequence  QDLIRLLMTDNPELRPTVAEVMVHPW
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Template Sequence  KRLMAECLKKKRDERPLFPQILASIE
Template Known Secondary structure  T
SSGGGS

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   690.........700.........710.....
 
Download:Text version FASTA version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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