Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 313 Aligned Residues 229 % Identity 21% Template c3c1xA_ PDB info PDB header:transferase Chain: A: PDB Molecule:hepatocyte growth factor receptor; PDBTitle: crystal structure of the tyrosine kinase domain of the2 hepatocyte growth factor receptor c-met in complex with a3 pyrrolotriazine based inhibitor Resolution 2.17 Å

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		8	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.				.	.	.	.	.	.	40	.			.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.
Predicted Secondary structure																												.	.	.									.	.
Query SS confidence																												.	.	.									.	.
Query Sequence		Y	E	M	L	E	T	I	G	Q	G	G	C	A	Q	V	K	L	A	Q	H	R	L	T	G	T	H	.	.	.	V	A	V	K	V	I	V	K	.	.	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T	D	H	P
Query Conservation																												.	.	.									.	.
Alig confidence																												.	.	.									.	.
Template Conservation
Template Sequence		V	H	F	N	E	V	I	G	R	G	H	F	G	C	V	Y	H	G	T	L	L	D	N	D	G	K	K	I	H	C	A	V	K	S	L	N	R	I	T	D	I	G	E	V	S	Q	F	L	T	E	G	I	I	M	K	D	F	S	H	P
Template Known Secondary structure												S	S	S										T	T	T												S		S		S											T	T	S	T	T				T
Template Predicted Secondary structure
Template SS confidence
		1078	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.
		63	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.			.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Predicted Secondary structure																																		.	.
Query SS confidence																																		.	.
Query Sequence		N	I	I	S	L	L	Q	V	I	E	T	K	K	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	Q	.	.	N	A	G	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L	S	A	V	N	Y	C	H	N
Query Conservation																																		.	.
Alig confidence																																		.	.
Template Conservation
Template Sequence		N	V	L	S	L	L	G	I	C	L	R	S	E	G	S	P	L	V	V	L	P	Y	M	K	H	G	D	L	R	N	F	I	R	N	E	T	H	N	P	T	V	K	D	L	I	G	F	G	L	Q	V	A	K	G	M	K	F	L	A	S
Template Known Secondary structure		T	B											S	S										T	T		B								T	T				B
Template Predicted Secondary structure
Template SS confidence
		1138	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.
		121	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	G	I	V	H	R	D	L	T	P	D	N	I	M	V	E	K	D	G	K	V	K	I	I	D	F	G	L	G	T	Q	E	K	P	A	Q	K	L	N	L	F	C	E	N	Y	P	F	S	T	P	E	V	L	L	S	R	P	Y	D	M
Query Conservation
Alig confidence																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.
Template Conservation																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.
Template Sequence		K	K	F	V	H	R	D	L	A	A	R	N	C	M	L	D	E	K	F	T	V	K	V	A	D	F	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	P	V	K	W	M	A	L	E	S	L	Q	T	Q	K	F	.	T
Template Known Secondary structure		T	T				S				G	G	G					T	T									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.			G	G	G	S											.
Template Predicted Secondary structure																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.
Template SS confidence
		1198	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.																	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.		1240
		181	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.		.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.		.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
Predicted Secondary structure																			.																					.
Query SS confidence																			.																					.
Query Sequence		R	K	I	D	V	W	G	L	G	V	V	L	Y	F	M	V	T	.	G	K	I	L	F	D	A	A	S	I	E	K	L	R	K	Q	I	V	A	G	.	K	C	S	V	P	C	R	L	S	V	E	L	Q	D	L	I	R	L	L	M	T
Query Conservation																			.																					.
Alig confidence																			.																					.
Template Conservation
Template Sequence		T	K	S	D	V	W	S	F	G	V	L	L	W	E	L	M	T	R	G	A	P	P	Y	P	D	V	N	T	F	D	I	T	V	Y	L	L	Q	G	R	R	L	L	Q	P	E	Y	C	P	D	P	L	Y	E	V	M	L	K	C	W	H
Template Known Secondary structure																		T	T	S			S		T	T	S		S	S								T	T							T	T													T
Template Predicted Secondary structure
Template SS confidence
		1262	.	.	.	.	.	.	.	1270	.	.	.	.	.	.	.	.	.	1280	.	.	.	.	.	.	.	.	.	1290	.	.	.	.	.	.	.	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	N	P	E	L	R	P	T	V	A	E	V	M	V	H
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	K	A	E	M	R	P	S	F	S	E	L	V	S	R
Template Known Secondary structure		S	S	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		1322	.	.	.	.	.	.	.	1330	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D