Job Description A0JLX3 Confidence 100.00% Date Wed Jul 10 14:37:17 BST 2013 Rank 261 Aligned Residues 250 % Identity 26% Template c2pvmA_ PDB info PDB header:transferase Chain: A: PDB Molecule:casein kinase ii subunit alpha; PDBTitle: structure-based design of pyrazolo[1,5-a][1,3,5]triazine2 derivatives as potent inhibitors of protein kinase ck2 Resolution 2.00 Å

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		4	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	H	A	Q	Y	E	M	L	E	T	I	G	Q	G	G	C	A	Q	V	K	L	A	Q	H	R	L	T	G	T	H	V	A	V	K	V	I	V	K	R	E	C	W	F	N	P	V	M	S	E	A	E	L	L	M	M	T	D	H	P	N
Query Conservation
Alig confidence																																									.	.
Template Conservation																																									.	.
Template Sequence		E	Q	D	D	Y	E	V	V	R	K	V	G	R	G	K	Y	S	E	V	F	E	G	I	N	V	N	N	N	E	K	C	I	I	K	I	L	K	P	V	.	.	K	K	K	K	I	K	R	E	I	K	I	L	Q	N	L	G	G	P	N
Template Known Secondary structure			G	G	G											S	S									T	T	T											S		.	.																		T	T
Template Predicted Secondary structure																																									.	.
Template SS confidence
		35	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.			.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.
		64	.	.	.	.	.	70	.	.	.			.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.
Predicted Secondary structure												.	.
Query SS confidence												.	.
Query Sequence		I	I	S	L	L	Q	V	I	E	T	.	.	K	K	K	L	Y	L	I	M	E	L	C	E	G	K	S	L	Y	Q	H	I	Q	N	A	G	Y	L	Q	E	D	E	A	C	P	L	F	K	Q	L	L	S	A	V	N	Y	C	H	N	Q
Query Conservation												.	.
Alig confidence												.	.																						.	.	.
Template Conservation																																			.	.	.
Template Sequence		I	V	K	L	L	D	I	V	R	D	Q	H	S	K	T	P	S	L	I	F	E	Y	V	N	N	T	D	F	K	V	L	Y	P	.	.	.	T	L	T	D	Y	D	I	R	Y	Y	I	Y	E	L	L	K	A	L	D	Y	C	H	S	Q
Template Known Secondary structure		B										T	T	T																			G	G	.	.	.	G																							T
Template Predicted Secondary structure																																			.	.	.
Template SS confidence
		94	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.				.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150
		122	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.		.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Predicted Secondary structure																			.
Query SS confidence																			.
Query Sequence		G	I	V	H	R	D	L	T	P	D	N	I	M	V	E	K	D	.	G	K	V	K	I	I	D	F	G	L	G	T	Q	E	K	P	A	Q	K	L	N	L	F	C	E	N	Y	P	F	S	T	P	E	V	L	L	S	R	P	Y	D	M
Query Conservation																			.
Alig confidence																			.
Template Conservation
Template Sequence		G	I	M	H	R	D	V	K	P	H	N	V	M	I	D	H	E	L	R	K	L	R	L	I	D	W	G	L	A	E	F	Y	H	P	G	K	E	Y	N	V	R	V	A	S	R	Y	F	K	G	P	E	L	L	V	D	L	Q	D	Y	D
Template Known Secondary structure		T							S	G	G	G					T	T	T	T								T	T						T	T					S			S		G	G	G							T	T			S
Template Predicted Secondary structure
Template SS confidence
		151	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
		181	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.		.	.	.	.	.	.	.	210	.	.	.	.	.	.
Predicted Secondary structure																								.															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																								.															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		R	K	I	D	V	W	G	L	G	V	V	L	Y	F	M	V	T	G	K	I	L	F	.	D	A	A	S	I	E	K	L	R	K	Q	I	V	A	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																								.															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																								.															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		Y	S	L	D	M	W	S	L	G	C	M	F	A	G	M	I	F	R	K	E	P	F	F	Y	G	H	D	N	H	D	Q	L	V	K	I	A	K	V	L	G	T	D	G	L	N	A	Y	L	N	K	Y	R	I	E	L	D	P	Q	L	E
Template Known Secondary structure		T																	T		S	S	S	S			S	S																								T	T
Template Predicted Secondary structure
Template SS confidence
		211	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270
																217	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	K	C	S	V	P	C	R	L	S	V	E	L	Q	D	L	I	R	L	L	M	T	D	N	P	E	L	R	P	T	V	A	E	V	M	V	H	P	W	V	T	E
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		A	L	V	G	R	H	S	R	K	P	W	L	K	F	M	N	A	D	N	Q	H	L	V	S	P	E	A	I	D	F	L	D	K	L	L	R	Y	D	H	Q	E	R	L	T	A	L	E	A	M	T	H	P	Y	F	Q	Q
Template Known Secondary structure												G	G	G	G			T	T	T	G	G	G											T	T			S	S	T	T	T	S									S	G	G	G
Template Predicted Secondary structure
Template SS confidence
		271	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions	Phyre2 is part of Genome3D