Phyre 2 Results for A2A3V2

Email	l.a.kelley@imperial.ac.uk
Description	A2A3V2
Date	Wed Jul 10 14:16:38 BST 2013
Unique Job ID	4164983c15199da1
Sequence	MATWRRDGRL ... Download FASTA

Summary

Top model

Image coloured by rainbow N → C terminus

Model dimensions (Å):

X:50.985 Y:46.773 Z:62.152

Model (left) based on template d1okca_

Top template information

Fold:Mitochondrial carrier
Superfamily:Mitochondrial carrier
Family:Mitochondrial carrier

Confidence and coverage

Confidence:

100.0%

Coverage:

82%

278 residues ( 82% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M A T W R R D G R L T G S Q R L L C A G L A G A F S L S L T A P L E L A T V L A Q V G K V Q S H S L G L W A T G R R V W

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence L S E G P R A L W K G N G V A C L R L F P C S M V Q L A A Y R K F V V L F M D D L G R I S Q W S S I V T G S L A G M V S

Secondary structure

SS confidence

Disorder
? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence T I V T Y P T D L I K T R L M V Q N V L E P S Y R G L I H A F S T I Y Q Q E G F L A L Y R G V S L T V L G A V P F S A G

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence S L L V Y M N L E K V W N G P R D R F S H L Q N F A N V C V A A A V S Q T L S F P F D T V K R K M Q A Q S P Y L P H Y G

Secondary structure

SS confidence

Disorder
? ? ?
? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence G V D V H F S G A A D C F R Q I V K T Q G V L G L W N G L T A N L L K V V P Y F G V M F S M F E F C K R I F L Y Q N G Y

Secondary structure

SS confidence

Disorder ? ? ?
? ? ? ?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 .

Sequence T L S P L T Y K L T P G V D Q S L K P Q E L R E L K K F F K R R K L H S K T P P W

Secondary structure

SS confidence

Disorder ? ? ? ?
? ? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered ( 18%)

Alpha helix ( 74%)

Beta strand ( 0%)

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 1okc chain A

Region: 7 - 290
Aligned: 278
Modelled: 284
Confidence: 100.0%
Identity: 26%
Fold: Mitochondrial carrier
Superfamily: Mitochondrial carrier
Family: Mitochondrial carrier

Phyre2

PDB 2lck chain A

Region: 15 - 294
Aligned: 271
Modelled: 280
Confidence: 100.0%
Identity: 23%
PDB header:transport protein
Chain: A: PDB Molecule:mitochondrial uncoupling protein 2;
PDBTitle: structure of the mitochondrial uncoupling protein 2 determined by nmr2 molecular fragment replacement

Phyre2

PDB 1bcc chain G

Region: 259 - 298
Aligned: 40
Modelled: 40
Confidence: 45.4%
Identity: 25%
Fold: Single transmembrane helix
Superfamily: Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
Family: Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)

Phyre2

PDB 3cwb chain T

Region: 259 - 298
Aligned: 40
Modelled: 40
Confidence: 44.6%
Identity: 15%
PDB header:oxidoreductase
Chain: T: PDB Molecule:mitochondrial ubiquinol-cytochrome c reductase ubiquinone-
PDBTitle: chicken cytochrome bc1 complex inhibited by an iodinated analogue of2 the polyketide crocacin-d

Phyre2

PDB 1ppj chain G

Region: 259 - 296
Aligned: 38
Modelled: 38
Confidence: 33.5%
Identity: 18%
Fold: Single transmembrane helix
Superfamily: Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
Family: Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)

Phyre2

PDB 2z2f chain A

Region: 250 - 264
Aligned: 15
Modelled: 15
Confidence: 18.9%
Identity: 33%
PDB header:hydrolase
Chain: A: PDB Molecule:lysozyme c-2;
PDBTitle: x-ray crystal structure of bovine stomach lysozyme

Phyre2

PDB 1gd6 chain A

Region: 250 - 264
Aligned: 15
Modelled: 15
Confidence: 17.2%
Identity: 27%
Fold: Lysozyme-like
Superfamily: Lysozyme-like
Family: C-type lysozyme

Phyre2

PDB 1f6s chain A

Region: 250 - 264
Aligned: 15
Modelled: 15
Confidence: 15.4%
Identity: 20%
Fold: Lysozyme-like
Superfamily: Lysozyme-like
Family: C-type lysozyme

Phyre2

PDB 1yro chain A domain 1

Region: 250 - 264
Aligned: 15
Modelled: 15
Confidence: 15.2%
Identity: 20%
Fold: Lysozyme-like
Superfamily: Lysozyme-like
Family: C-type lysozyme

Phyre2

PDB 1fkq chain A

Region: 250 - 264
Aligned: 15
Modelled: 15
Confidence: 14.7%
Identity: 20%
Fold: Lysozyme-like
Superfamily: Lysozyme-like
Family: C-type lysozyme

Phyre2

PDB 1alc chain A

Region: 250 - 264
Aligned: 15
Modelled: 15
Confidence: 14.0%
Identity: 20%
Fold: Lysozyme-like
Superfamily: Lysozyme-like
Family: C-type lysozyme

Phyre2

PDB 3cx5 chain H domain 1

Region: 259 - 299
Aligned: 41
Modelled: 41
Confidence: 13.6%
Identity: 10%
Fold: Single transmembrane helix
Superfamily: Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
Family: Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)

Phyre2

PDB 1iiz chain A

Region: 250 - 264
Aligned: 15
Modelled: 15
Confidence: 12.2%
Identity: 20%
Fold: Lysozyme-like
Superfamily: Lysozyme-like
Family: C-type lysozyme

Phyre2

PDB 2fbd chain B

Region: 250 - 264
Aligned: 15
Modelled: 15
Confidence: 11.9%
Identity: 33%
PDB header:hydrolase
Chain: B: PDB Molecule:lysozyme 1;
PDBTitle: the crystallographic structure of the digestive lysozyme 1 from musca2 domestica at 1.90 ang.

Phyre2

PDB 1b9o chain A

Region: 250 - 266
Aligned: 17
Modelled: 17
Confidence: 10.7%
Identity: 18%
Fold: Lysozyme-like
Superfamily: Lysozyme-like
Family: C-type lysozyme

Phyre2

PDB 1ghl chain A

Region: 250 - 264
Aligned: 15
Modelled: 15
Confidence: 9.8%
Identity: 27%
Fold: Lysozyme-like
Superfamily: Lysozyme-like
Family: C-type lysozyme

Phyre2

PDB 1hfx chain A

Region: 250 - 266
Aligned: 17
Modelled: 17
Confidence: 9.7%
Identity: 18%
Fold: Lysozyme-like
Superfamily: Lysozyme-like
Family: C-type lysozyme

Phyre2

PDB 2d7v chain A domain 1

Region: 5 - 31
Aligned: 27
Modelled: 27
Confidence: 8.9%
Identity: 11%
Fold: OsmC-like
Superfamily: OsmC-like
Family: Ohr/OsmC resistance proteins

Phyre2

PDB 1lsg chain A domain 1

Region: 250 - 264
Aligned: 15
Modelled: 15
Confidence: 8.7%
Identity: 27%
Fold: Lysozyme-like
Superfamily: Lysozyme-like
Family: C-type lysozyme

Phyre2

PDB 2oso chain A domain 1

Region: 15 - 47
Aligned: 33
Modelled: 33
Confidence: 8.7%
Identity: 12%
Fold: Ligand-binding domain in the NO signalling and Golgi transport
Superfamily: Ligand-binding domain in the NO signalling and Golgi transport
Family: MJ1460-like

Phyre2

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	A	T	W	R	R	D	G	R	L	T	G	S	Q	R	L	L	C	A	G	L	A	G	A	F	S	L	S	L	T	A	P	L	E	L	A	T	V	L	A	Q	V	G	K	V	Q	S	H	S	L	G	L	W	A	T	G	R	R	V	W
Secondary structure
SS confidence
Disorder	?	?	?	?	?	?	?	?	?	?																																	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	L	S	E	G	P	R	A	L	W	K	G	N	G	V	A	C	L	R	L	F	P	C	S	M	V	Q	L	A	A	Y	R	K	F	V	V	L	F	M	D	D	L	G	R	I	S	Q	W	S	S	I	V	T	G	S	L	A	G	M	V	S
Secondary structure
SS confidence
Disorder																																									?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	T	I	V	T	Y	P	T	D	L	I	K	T	R	L	M	V	Q	N	V	L	E	P	S	Y	R	G	L	I	H	A	F	S	T	I	Y	Q	Q	E	G	F	L	A	L	Y	R	G	V	S	L	T	V	L	G	A	V	P	F	S	A	G
Secondary structure
SS confidence
Disorder																	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence	S	L	L	V	Y	M	N	L	E	K	V	W	N	G	P	R	D	R	F	S	H	L	Q	N	F	A	N	V	C	V	A	A	A	V	S	Q	T	L	S	F	P	F	D	T	V	K	R	K	M	Q	A	Q	S	P	Y	L	P	H	Y	G
Secondary structure
SS confidence
Disorder																?	?	?																																	?	?	?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence	G	V	D	V	H	F	S	G	A	A	D	C	F	R	Q	I	V	K	T	Q	G	V	L	G	L	W	N	G	L	T	A	N	L	L	K	V	V	P	Y	F	G	V	M	F	S	M	F	E	F	C	K	R	I	F	L	Y	Q	N	G	Y
Secondary structure
SS confidence
Disorder	?	?	?																																																						?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.
Sequence	T	L	S	P	L	T	Y	K	L	T	P	G	V	D	Q	S	L	K	P	Q	E	L	R	E	L	K	K	F	F	K	R	R	K	L	H	S	K	T	P	P	W
Secondary structure
SS confidence
Disorder	?	?	?	?																														?	?	?	?	?	?	?	?
Disorder confidence