|   |
1149 | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | N | K | V | G | C | N | P | N | E | D | V | A | I | F | A | V | D | S | L | R | Q | L | S | M | K | F | L | E | K | G | E | L | A | N | F | R | F | Q | K | D | F | L | R | P | F | E | H | I | M | K | K | N | R | S | P | T | I | R | D |
Query Conservation |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|
|
|   |
|   |
|
|   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|
|   |   |   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|   |
|   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|
| . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
M | I | E | M | I | F | S | K | S | P | E | Q | Q | L | S | A | T | Q | K | F | R | K | L | L | . |
S | K | E | P | N | P | P | I | D | E | V | I | S | T | P | G | V | V | A | R | F | V | E | F | L | K | R | K | E | N | C | T | L | Q | F |
Template Known Secondary structure |   |
 |  |  |  |  | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | T | S | S | S |
|
|
|  |  |  |  |  | T | S | T | T |
|  |  |  |  |  |  |  | T | T |
| T | T |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
87 | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | |
. | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . |
  |
  |   |
1209 | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . | . | |
. | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . | 1260 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | V | I | R | C | I | A | Q | M | V | S | S | Q | A | A | N | I | R | S | . |
G | W | K | N | I | F | A | V | F | H | Q | A | A | S | D | H | D | G | N | I | V | E | L | A | F | Q | T | T | G | H | I | V | S | T | I | F | Q | H | H | F |
Query Conservation |   |
  |
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |
|   |
| . |
|
|   |   |
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |
|
|   |   |
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |
|   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . |
Template Sequence |   |
E | S | A | W | V | L | T | N | I | A | S | G | N | S | L | Q | T | R | I | V | I | Q | A | G | A | V | P | I | F | I | E | L | L | S | S | E | F | E | D | V | Q | E | Q | A | V | W | A | L | G | N | I | A | G | D | S | T | M | C | R | . |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | |
  |
  |   |
1268 | . | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . | . | . | . | . | . | . | 1300 | . | . | . | . | . | . | . | . | . | 1310 | . | . | . | . | . | . | . | . | . | 1320 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | A | A | I | D | S | F | Q | D | A | V | K | C | L | S | E | F | A | C | N | A | A | F | P | D | T | S | M | E | A | I | R | L | I | R | F | C | G | K | Y | V | S | E | R | P | R | V | L | Q | E | Y | T | S | D | D | M | N | V | A | P |
Query Conservation |   |
  |   |   |   |   |   |
|   |
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
D | Y | V | L | D | C | N | I | L | P | P | L | L | Q | L | F | S | K | Q | N | R | L | T | M | T | R | N | A | V | W | A | L | S | N | L | C | R | G | K | S | P | P | P | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . |  |  |  |  |  | T | T |
|  |  |  |  |  |  | T | T | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S | S |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
205 | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
1328 | . | 1330 | . | . | . | . | . | . | . | . | . | 1340 | . | . | . | . | . | . | . | . | . | 1350 | . | . | . | . | . | . | . | . | . | 1360 | . | . | . | . | . | . | . | . | . | 1370 | . | . | . | . | . | . | . | . | . | 1380 | . | . | . | |
. | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
Query Sequence |   |
G | D | R | V | W | V | R | G | W | F | P | I | L | F | E | L | S | C | I | I | N | R | C | K | L | D | V | R | T | R | G | L | T | V | M | F | E | I | M | K | S | Y | G | H | T | F | A | K | H | W | W | Q | D | L | F | R | . |
I | V | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|
|
|   |   |
|   |   |
|   |   |
|   |
|   |
|
|
|   |   |
|
|   |
|
|
|   |
|
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   | . |
|
|
|
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
Template Conservation |   |
. | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
F | A | K | V | S | P | C | L | N | V | L | S | W | L | L | F | V | S | D | T | D | V | L | A | D | A | C | W | A | L | S | Y | L | S | D | G | . |
. |
. |
. |
. |
P | N | D | K | I | Q | A | V | I | D | A | G | V | C |
Template Known Secondary structure |   |
. | . | . | . | . |  |  |  |  | G | G | G |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  | T | T | T |  |
Template Predicted Secondary structure |   |
. | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
249 | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
  |
  |   |
1387 | . | . | 1390 | . | . | . | . | . | . | . | . | . | 1400 | . | . | . | . | . | . | . | . | . | 1410 | . | . | . | . | . | . | . | . | . | 1420 | . | . | . | . | . | . | . | . | . | 1430 | . | . | . | . | . | . | . | . | . | 1440 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | I | F | D | N | M | K | L | P | E | Q | Q | S | E | K | S | E | W | M | T | T | T | C | N | H | A | L | Y | A | I | C | D | V | F | T | Q | F | Y | E | A | L | H | E | V | L | L | S | D | V | F | A | Q | L | Q | W | C | V | K | Q | D |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |
|   |
|
|   |   |
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
R | R | L | V | E | L | L | M | H | N | D | Y | . |
. |
. |
. |
. |
. |
. |
. |
K | V | V | S | P | A | L | R | A | V | G | N | I | V | T | G | D | D | I | Q | T | Q | V | I | L | N | C | S | A | L | Q | S | L | L | H | L | L | S | S | P |
Template Known Secondary structure |   |
 |  |  |  |  | G | G | G |
| S |
|  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  | T | T |
| S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
299 | 300 | . | . | . | . | . | . | . | . | . | 310 | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 |
  |
  |   |
1447 | . | . | 1450 | . | . | . | . | . | . | . | . | . | 1460 | . | . | . | . | . | . | . | . | . | 1470 | . | . | . | . | . | . | . | . | . | 1480 | . | . | . | . | . | . | . | . | . | 1490 |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | E | Q | L | A | R | S | G | T | N | C | L | E | N | L | V | I | S | N | G | E | K | F | S | P | A | V | W | D | E | T | C | N | C | M | L | D | I | F | K | T | T | I | P |
Query Conservation |   |
  |
|   |
|
|
|   |
|   |   |
|
|   |   |
|
|   |   |   |
|   |   |
|
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
Template Sequence |   |
K | E | S | I | K | K | E | A | C | W | T | I | S | N | I | T | A | G | N | R | A | Q | I | Q | T | V | I | D | A | N | I | F | P | A | L | I | S | I | L | Q | T | A | E | F |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  | S |
|  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
351 | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . |
  |