Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ96FX8
DateFri May 25 09:35:23 BST 2012
Unique Job IDe3d5bae4829733c1

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3b8eB_
Top template information
PDB header:hydrolase/transport protein
Chain: B: PDB Molecule:sodium/potassium-transporting atpase subunit
PDBTitle: crystal structure of the sodium-potassium pump
Confidence and coverage
Confidence: 21.2% Coverage: 20%
38 residues ( 20% of your sequence) have been modelled with 21.2% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
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3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MIRCGLACERCRWILPLLLLSAIAFDIIALAGRGWLQSSDHGQTSSLWWKCSQEGGGSGS
Secondary structure 




















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Disorder  ?????














































????????
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   .........70.........80.........90.........100.........110.........120
Sequence  YEEGCQSLMEYAWGRAAAAMLFCGFIILVICFILSFFALCGPQMLVFLRVIGGLLALAAV
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Disorder  ?








??















































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   .........130.........140.........150.........160.........170.........180
Sequence  FQIISLVIYPVKYTQTFTLHANPAVTYIYNWAYGFGWAATIILIGCAFFFCCLPNYEDDL
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???

??



































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   .........190...
Sequence  LGNAKPRYFYTSA
Secondary structure 










SS confidence 












Disorder 





???????
Disorder confidence 












 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3b8e chain B

3D model

Region: 150 - 188
Aligned: 38
Modelled: 39
Confidence: 21.2%
Identity: 13%
PDB header:hydrolase/transport protein
Chain: B: PDB Molecule:sodium/potassium-transporting atpase subunit
PDBTitle: crystal structure of the sodium-potassium pump

Phyre2

PDB 3rko chain L

3D model

Region: 83 - 189
Aligned: 105
Modelled: 107
Confidence: 19.7%
Identity: 17%
PDB header:oxidoreductase
Chain: L: PDB Molecule:nadh-quinone oxidoreductase subunit l;
PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution

Phyre2

PDB 2pm5 chain B

3D model

Region: 44 - 51
Aligned: 8
Modelled: 8
Confidence: 12.3%
Identity: 38%
PDB header:antimicrobial protein
Chain: B: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1) (defensin, alpha
PDBTitle: human alpha-defensin 1 derivative (hnp1)

Phyre2

PDB 2pm5 chain A

3D model

Region: 44 - 51
Aligned: 8
Modelled: 8
Confidence: 12.3%
Identity: 38%
PDB header:antimicrobial protein
Chain: A: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1) (defensin, alpha
PDBTitle: human alpha-defensin 1 derivative (hnp1)

Phyre2

PDB 2pm1 chain A

3D model

Region: 44 - 51
Aligned: 8
Modelled: 8
Confidence: 12.3%
Identity: 38%
PDB header:antimicrobial protein
Chain: A: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1)
PDBTitle: derivative of human alpha-defensin 1 (hnp1)

Phyre2

PDB 2wwa chain C

3D model

Region: 10 - 34
Aligned: 25
Modelled: 21
Confidence: 10.9%
Identity: 28%
PDB header:ribosome
Chain: C: PDB Molecule:protein transport protein seb2;
PDBTitle: cryo-em structure of idle yeast ssh1 complex bound to the2 yeast 80s ribosome

Phyre2

PDB 3jrt chain A

3D model

Region: 5 - 54
Aligned: 49
Modelled: 50
Confidence: 10.0%
Identity: 18%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:integron cassette protein vpc_cass2;
PDBTitle: structure from the mobile metagenome of v. paracholerae:2 integron cassette protein vpc_cass2

Phyre2

PDB 3hie chain A

3D model

Region: 173 - 188
Aligned: 16
Modelled: 16
Confidence: 9.4%
Identity: 31%
PDB header:exocytosis
Chain: A: PDB Molecule:exocyst complex component sec3;
PDBTitle: structure of the membrane-binding domain of the sec3 subunit2 of the exocyst complex

Phyre2

PDB 1mct chain I

3D model

Region: 47 - 61
Aligned: 15
Modelled: 15
Confidence: 9.0%
Identity: 13%
PDB header:complex(proteinase/inhibitor)
Chain: I: PDB Molecule:trypsin inhibitor a;
PDBTitle: the refined 1.6 angstroms resolution crystal structure of2 the complex formed between porcine beta-trypsin and mcti-a,3 a trypsin inhibitor of squash family

Phyre2

PDB 1mct chain I

3D model

Region: 47 - 61
Aligned: 15
Modelled: 15
Confidence: 9.0%
Identity: 13%
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: Plant inhibitors of proteinases and amylases
Family: Plant inhibitors of proteinases and amylases

Phyre2

PDB 2w8a chain C

3D model

Region: 116 - 192
Aligned: 76
Modelled: 77
Confidence: 7.1%
Identity: 14%
PDB header:membrane protein
Chain: C: PDB Molecule:glycine betaine transporter betp;
PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate

Phyre2

PDB 3a58 chain A

3D model

Region: 173 - 189
Aligned: 17
Modelled: 17
Confidence: 6.8%
Identity: 29%
PDB header:protein transport/exocytosis
Chain: A: PDB Molecule:exocyst complex component sec3;
PDBTitle: crystal structure of sec3p - rho1p complex from2 saccharomyces cerevisiae

Phyre2

PDB 1dtx chain A

3D model

Region: 172 - 193
Aligned: 22
Modelled: 22
Confidence: 6.2%
Identity: 14%
Fold: BPTI-like
Superfamily: BPTI-like
Family: Small Kunitz-type inhibitors & BPTI-like toxins

Phyre2

PDB 1j4n chain A

3D model

Region: 81 - 185
Aligned: 102
Modelled: 105
Confidence: 6.2%
Identity: 11%
Fold: Aquaporin-like
Superfamily: Aquaporin-like
Family: Aquaporin-like

Phyre2

PDB 1f2s chain I

3D model

Region: 47 - 61
Aligned: 15
Modelled: 15
Confidence: 5.6%
Identity: 13%
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: Plant inhibitors of proteinases and amylases
Family: Plant inhibitors of proteinases and amylases

Phyre2

PDB 1f2s chain I

3D model

Region: 47 - 61
Aligned: 15
Modelled: 15
Confidence: 5.6%
Identity: 13%
PDB header:hydrolase/hydrolase inhibitor
Chain: I: PDB Molecule:trypsin inhibitor a;
PDBTitle: crystal structure of the complex formed between bovine beta-2 trypsin and mcti-a, a trypsin inhibitor of squash family3 at 1.8 a resolution

Phyre2

PDB 2oyy chain F

3D model

Region: 14 - 35
Aligned: 22
Modelled: 22
Confidence: 5.2%
Identity: 27%
PDB header:unknown function
Chain: F: PDB Molecule:hexameric cytochrome;
PDBTitle: hthp: a hexameric tyrosine-coordinated heme protein

Phyre2

PDB 1itu chain A

3D model

Region: 174 - 192
Aligned: 19
Modelled: 19
Confidence: 5.1%
Identity: 37%
Fold: TIM beta/alpha-barrel
Superfamily: Metallo-dependent hydrolases
Family: Renal dipeptidase

Phyre2

PDB 2ctu chain A

3D model

Region: 3 - 11
Aligned: 9
Modelled: 9
Confidence: 5.1%
Identity: 33%
PDB header:transcription
Chain: A: PDB Molecule:zinc finger protein 483;
PDBTitle: solution structure of zinc finger domain from human zn2 finger protein 483

Phyre2
1

c3b8eB_
2

c3rkoL_
3

c2pm5B_
4

c2pm5A_
5

c2pm1A_
6

c2wwaC_
7

c3jrtA_
8

c3hieA_
9

c1mctI_
10

d1mcti_
11

c2w8aC_
12

c3a58A_
13

d1dtxa_
14

d1j4na_
15

d1f2si_
16

c1f2sI_
17

c2oyyF_
18

d1itua_
19

c2ctuA_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3b8eB_



21.2 13 PDB header:hydrolase/transport protein
Chain: B: PDB Molecule:sodium/potassium-transporting atpase subunit
PDBTitle: crystal structure of the sodium-potassium pump
2c3rkoL_



19.7 17 PDB header:oxidoreductase
Chain: L: PDB Molecule:nadh-quinone oxidoreductase subunit l;
PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution
3c2pm5B_



12.3 38 PDB header:antimicrobial protein
Chain: B: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1) (defensin, alpha
PDBTitle: human alpha-defensin 1 derivative (hnp1)
4c2pm5A_



12.3 38 PDB header:antimicrobial protein
Chain: A: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1) (defensin, alpha
PDBTitle: human alpha-defensin 1 derivative (hnp1)
5c2pm1A_



12.3 38 PDB header:antimicrobial protein
Chain: A: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1)
PDBTitle: derivative of human alpha-defensin 1 (hnp1)
6c2wwaC_



10.9 28 PDB header:ribosome
Chain: C: PDB Molecule:protein transport protein seb2;
PDBTitle: cryo-em structure of idle yeast ssh1 complex bound to the2 yeast 80s ribosome
7c3jrtA_



10.0 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:integron cassette protein vpc_cass2;
PDBTitle: structure from the mobile metagenome of v. paracholerae:2 integron cassette protein vpc_cass2
8c3hieA_



9.4 31 PDB header:exocytosis
Chain: A: PDB Molecule:exocyst complex component sec3;
PDBTitle: structure of the membrane-binding domain of the sec3 subunit2 of the exocyst complex
9c1mctI_



9.0 13 PDB header:complex(proteinase/inhibitor)
Chain: I: PDB Molecule:trypsin inhibitor a;
PDBTitle: the refined 1.6 angstroms resolution crystal structure of2 the complex formed between porcine beta-trypsin and mcti-a,3 a trypsin inhibitor of squash family
10d1mcti_



9.0 13 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:Plant inhibitors of proteinases and amylases
Family:Plant inhibitors of proteinases and amylases
11c2w8aC_



7.1 14 PDB header:membrane protein
Chain: C: PDB Molecule:glycine betaine transporter betp;
PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate
12c3a58A_



6.8 29 PDB header:protein transport/exocytosis
Chain: A: PDB Molecule:exocyst complex component sec3;
PDBTitle: crystal structure of sec3p - rho1p complex from2 saccharomyces cerevisiae
13d1dtxa_



6.2 14 Fold:BPTI-like
Superfamily:BPTI-like
Family:Small Kunitz-type inhibitors & BPTI-like toxins
14d1j4na_



6.2 11 Fold:Aquaporin-like
Superfamily:Aquaporin-like
Family:Aquaporin-like
15d1f2si_



5.6 13 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:Plant inhibitors of proteinases and amylases
Family:Plant inhibitors of proteinases and amylases
16c1f2sI_



5.6 13 PDB header:hydrolase/hydrolase inhibitor
Chain: I: PDB Molecule:trypsin inhibitor a;
PDBTitle: crystal structure of the complex formed between bovine beta-2 trypsin and mcti-a, a trypsin inhibitor of squash family3 at 1.8 a resolution
17c2oyyF_



5.2 27 PDB header:unknown function
Chain: F: PDB Molecule:hexameric cytochrome;
PDBTitle: hthp: a hexameric tyrosine-coordinated heme protein
18d1itua_



5.1 37 Fold:TIM beta/alpha-barrel
Superfamily:Metallo-dependent hydrolases
Family:Renal dipeptidase
19c2ctuA_



5.1 33 PDB header:transcription
Chain: A: PDB Molecule:zinc finger protein 483;
PDBTitle: solution structure of zinc finger domain from human zn2 finger protein 483

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite