Phyre 2 Results for Q96FX8

Email	l.a.kelley@imperial.ac.uk
Description	Q96FX8
Date	Fri May 25 09:35:23 BST 2012
Unique Job ID	e3d5bae4829733c1

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c3b8eB_

Top template information

PDB header:hydrolase/transport protein
Chain: B: PDB Molecule:sodium/potassium-transporting atpase subunit
PDBTitle: crystal structure of the sodium-potassium pump

Confidence and coverage

Confidence:

21.2%

Coverage:

20%

38 residues ( 20% of your sequence) have been modelled with 21.2% confidence by the single highest scoring template.

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3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M I R C G L A C E R C R W I L P L L L L S A I A F D I I A L A G R G W L Q S S D H G Q T S S L W W K C S Q E G G G S G S

Secondary structure

SS confidence

Disorder ? ? ? ? ?
? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence Y E E G C Q S L M E Y A W G R A A A A M L F C G F I I L V I C F I L S F F A L C G P Q M L V F L R V I G G L L A L A A V

Secondary structure

SS confidence

Disorder ?
? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence F Q I I S L V I Y P V K Y T Q T F T L H A N P A V T Y I Y N W A Y G F G W A A T I I L I G C A F F F C C L P N Y E D D L

Secondary structure

SS confidence

Disorder
? ? ?
? ?

Disorder confidence

. . . . . . . . . 190 . . .

Sequence L G N A K P R Y F Y T S A

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 3b8e chain B

Region: 150 - 188
Aligned: 38
Modelled: 39
Confidence: 21.2%
Identity: 13%
PDB header:hydrolase/transport protein
Chain: B: PDB Molecule:sodium/potassium-transporting atpase subunit
PDBTitle: crystal structure of the sodium-potassium pump

Phyre2

PDB 3rko chain L

Region: 83 - 189
Aligned: 105
Modelled: 107
Confidence: 19.7%
Identity: 17%
PDB header:oxidoreductase
Chain: L: PDB Molecule:nadh-quinone oxidoreductase subunit l;
PDBTitle: crystal structure of the membrane domain of respiratory complex i from2 e. coli at 3.0 angstrom resolution

Phyre2

PDB 2pm5 chain B

Region: 44 - 51
Aligned: 8
Modelled: 8
Confidence: 12.3%
Identity: 38%
PDB header:antimicrobial protein
Chain: B: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1) (defensin, alpha
PDBTitle: human alpha-defensin 1 derivative (hnp1)

Phyre2

PDB 2pm5 chain A

Region: 44 - 51
Aligned: 8
Modelled: 8
Confidence: 12.3%
Identity: 38%
PDB header:antimicrobial protein
Chain: A: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1) (defensin, alpha
PDBTitle: human alpha-defensin 1 derivative (hnp1)

Phyre2

PDB 2pm1 chain A

Region: 44 - 51
Aligned: 8
Modelled: 8
Confidence: 12.3%
Identity: 38%
PDB header:antimicrobial protein
Chain: A: PDB Molecule:neutrophil defensin 1 (hnp-1) (hp-1) (hp1)
PDBTitle: derivative of human alpha-defensin 1 (hnp1)

Phyre2

PDB 2wwa chain C

Region: 10 - 34
Aligned: 25
Modelled: 21
Confidence: 10.9%
Identity: 28%
PDB header:ribosome
Chain: C: PDB Molecule:protein transport protein seb2;
PDBTitle: cryo-em structure of idle yeast ssh1 complex bound to the2 yeast 80s ribosome

Phyre2

PDB 3jrt chain A

Region: 5 - 54
Aligned: 49
Modelled: 50
Confidence: 10.0%
Identity: 18%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:integron cassette protein vpc_cass2;
PDBTitle: structure from the mobile metagenome of v. paracholerae:2 integron cassette protein vpc_cass2

Phyre2

PDB 3hie chain A

Region: 173 - 188
Aligned: 16
Modelled: 16
Confidence: 9.4%
Identity: 31%
PDB header:exocytosis
Chain: A: PDB Molecule:exocyst complex component sec3;
PDBTitle: structure of the membrane-binding domain of the sec3 subunit2 of the exocyst complex

Phyre2

PDB 1mct chain I

Region: 47 - 61
Aligned: 15
Modelled: 15
Confidence: 9.0%
Identity: 13%
PDB header:complex(proteinase/inhibitor)
Chain: I: PDB Molecule:trypsin inhibitor a;
PDBTitle: the refined 1.6 angstroms resolution crystal structure of2 the complex formed between porcine beta-trypsin and mcti-a,3 a trypsin inhibitor of squash family

Phyre2

PDB 1mct chain I

Region: 47 - 61
Aligned: 15
Modelled: 15
Confidence: 9.0%
Identity: 13%
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: Plant inhibitors of proteinases and amylases
Family: Plant inhibitors of proteinases and amylases

Phyre2

PDB 2w8a chain C

Region: 116 - 192
Aligned: 76
Modelled: 77
Confidence: 7.1%
Identity: 14%
PDB header:membrane protein
Chain: C: PDB Molecule:glycine betaine transporter betp;
PDBTitle: crystal structure of the sodium-coupled glycine betaine2 symporter betp from corynebacterium glutamicum with bound3 substrate

Phyre2

PDB 3a58 chain A

Region: 173 - 189
Aligned: 17
Modelled: 17
Confidence: 6.8%
Identity: 29%
PDB header:protein transport/exocytosis
Chain: A: PDB Molecule:exocyst complex component sec3;
PDBTitle: crystal structure of sec3p - rho1p complex from2 saccharomyces cerevisiae

Phyre2

PDB 1dtx chain A

Region: 172 - 193
Aligned: 22
Modelled: 22
Confidence: 6.2%
Identity: 14%
Fold: BPTI-like
Superfamily: BPTI-like
Family: Small Kunitz-type inhibitors & BPTI-like toxins

Phyre2

PDB 1j4n chain A

Region: 81 - 185
Aligned: 102
Modelled: 105
Confidence: 6.2%
Identity: 11%
Fold: Aquaporin-like
Superfamily: Aquaporin-like
Family: Aquaporin-like

Phyre2

PDB 1f2s chain I

Region: 47 - 61
Aligned: 15
Modelled: 15
Confidence: 5.6%
Identity: 13%
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: Plant inhibitors of proteinases and amylases
Family: Plant inhibitors of proteinases and amylases

Phyre2

PDB 1f2s chain I

Region: 47 - 61
Aligned: 15
Modelled: 15
Confidence: 5.6%
Identity: 13%
PDB header:hydrolase/hydrolase inhibitor
Chain: I: PDB Molecule:trypsin inhibitor a;
PDBTitle: crystal structure of the complex formed between bovine beta-2 trypsin and mcti-a, a trypsin inhibitor of squash family3 at 1.8 a resolution

Phyre2

PDB 2oyy chain F

Region: 14 - 35
Aligned: 22
Modelled: 22
Confidence: 5.2%
Identity: 27%
PDB header:unknown function
Chain: F: PDB Molecule:hexameric cytochrome;
PDBTitle: hthp: a hexameric tyrosine-coordinated heme protein

Phyre2

PDB 1itu chain A

Region: 174 - 192
Aligned: 19
Modelled: 19
Confidence: 5.1%
Identity: 37%
Fold: TIM beta/alpha-barrel
Superfamily: Metallo-dependent hydrolases
Family: Renal dipeptidase

Phyre2

PDB 2ctu chain A

Region: 3 - 11
Aligned: 9
Modelled: 9
Confidence: 5.1%
Identity: 33%
PDB header:transcription
Chain: A: PDB Molecule:zinc finger protein 483;
PDBTitle: solution structure of zinc finger domain from human zn2 finger protein 483

Phyre2

	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence	M	I	R	C	G	L	A	C	E	R	C	R	W	I	L	P	L	L	L	L	S	A	I	A	F	D	I	I	A	L	A	G	R	G	W	L	Q	S	S	D	H	G	Q	T	S	S	L	W	W	K	C	S	Q	E	G	G	G	S	G	S
Secondary structure
SS confidence
Disorder	?	?	?	?	?																																																?	?	?	?	?	?	?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence	Y	E	E	G	C	Q	S	L	M	E	Y	A	W	G	R	A	A	A	A	M	L	F	C	G	F	I	I	L	V	I	C	F	I	L	S	F	F	A	L	C	G	P	Q	M	L	V	F	L	R	V	I	G	G	L	L	A	L	A	A	V
Secondary structure
SS confidence
Disorder	?										?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence	F	Q	I	I	S	L	V	I	Y	P	V	K	Y	T	Q	T	F	T	L	H	A	N	P	A	V	T	Y	I	Y	N	W	A	Y	G	F	G	W	A	A	T	I	I	L	I	G	C	A	F	F	F	C	C	L	P	N	Y	E	D	D	L
Secondary structure
SS confidence
Disorder																		?	?	?			?	?
Disorder confidence

	.	.	.	.	.	.	.	.	.	190	.	.	.
Sequence	L	G	N	A	K	P	R	Y	F	Y	T	S	A
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?
Disorder confidence