| Query Index | . | . | . | . | : | . | . | . |   |   | . | 10 | . | . | . | . | : | . | . | . | . | 20 | . | . | . | . | : | . | . | . | . | 30 | . | . | . | . | : | . | . | . | . | 40 | . | . | . | . | : | . | . | . | . | 50 | . | . | . | . | : | . | . |   | . | . | 60 | . | . | . | . | : | . | . | . | . | 70 | . | . | . | . | : | . | . | . | . | 80 | . | . | . | . | : | . | . |   |   | . | . | 90 | . | . | . | . | : | . | . | . | . | 100 | . | . | . | . | : | . | . | . | . | 110 | . | . | . | . | : | . | . | . | . | 120 | . | . | . |   |   |   | . | : | . | . | . | . | 130 | . | . | . | . | : | . | . | . | . | 140 | . | . | . | . | : |   |   |   |   |   |   |   |
| Query Sequence Conservation 30 % | - | - | - | - | - | - | - | - |   |   | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |   | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |   |   | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |   |   |   | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |   |   |   |   |   |   |   |   |
| Query Sequence Conservation 40 % | - | - | - | - | - | - | - | - |   |   | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |   | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |   |   | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |   |   |   | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |   |   |   |   |   |   |   |   |
| Query Sequence Conservation 50 % | - | - | - | - | - | - | - | - |   |   | 8 | 6 | 6 | 1 | 1 | 5 | 1 | 1 | 2 | 2 | 3 | 2 | 8 | 2 | 1 | 3 | 3 | 2 | 2 | 1 | 2 | 1 | 1 | 9 | 3 | 2 | 2 | 1 | 1 | 1 | 6 | 7 | 1 | 1 | 1 | 1 | 1 | 8 | 1 | 1 | 9 | 10 | 1 | 1 | 2 | - | - | - | - |   | 1 | 1 | 2 | 1 | 3 | 1 | 3 | 4 | 3 | 2 | 9 | 1 | 1 | 2 | 1 | 2 | 1 | 8 | 5 | 1 | 1 | 1 | 2 | 1 | 1 | 6 | 9 | 4 | - | - |   |   | - | 5 | 1 | 1 | 3 | 1 | 1 | 2 | 0 | 2 | 3 | 1 | 7 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 3 | 1 | 10 | 2 | 1 | 1 | 1 | 3 | 1 | 4 | 1 | 1 | 5 | 8 | 9 | 2 |   |   |   | 3 | 1 | 8 | 1 | 1 | 1 | 1 | 1 | 1 | 8 | 4 | 1 | 9 | 3 | 2 | 5 | 2 | 7 | 1 | 2 | 5 | 10 |   |   |   |   |   |   |   |   |
| Query Sequence Conservation 60 % | - | - | - | - | - | - | - | 1 |   |   | 8 | 6 | 5 | 2 | 0 | 5 | 1 | 0 | 1 | 2 | 1 | 1 | 8 | 1 | 0 | 3 | 2 | 2 | 1 | 0 | 1 | 0 | 0 | 10 | 2 | 0 | 1 | 0 | 2 | 0 | 5 | 6 | 1 | 0 | 1 | 0 | 0 | 8 | 0 | 0 | 9 | 10 | 1 | 0 | 1 | 6 | 3 | 1 | 3 |   | 0 | 1 | 1 | 0 | 3 | 0 | 3 | 3 | 2 | 1 | 10 | 0 | 1 | 0 | 0 | 3 | 0 | 7 | 5 | 0 | 2 | 0 | 2 | 0 | 0 | 5 | 9 | 5 | - | - |   |   | - | 4 | 1 | 0 | 2 | 0 | 0 | 3 | 0 | 1 | 2 | 0 | 7 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 10 | 1 | 1 | 0 | 1 | 2 | 0 | 5 | 0 | 0 | 5 | 7 | 8 | 1 |   |   |   | 3 | 1 | 7 | 1 | 0 | 1 | 0 | 1 | 0 | 6 | 4 | 0 | 10 | 2 | 1 | 4 | 2 | 7 | 0 | 2 | 5 | 10 |   |   |   |   |   |   |   |   |
| Query Sequence Entropy (Normalised) | 2 | 2 | 1 | 2 | 1 | 1 | 1 | 1 |   |   | 2 | 3 | 1 | 2 | 2 | 3 | 1 | 1 | 3 | 1 | 1 | 1 | 9 | 1 | 2 | 2 | 1 | 0 | 3 | 1 | 1 | 1 | 1 | 4 | 1 | 1 | 1 | 3 | 1 | 3 | 3 | 4 | 1 | 1 | 2 | 5 | 3 | 2 | 2 | 1 | 3 | 6 | 1 | 2 | 4 | 2 | 2 | 2 | 2 |   | 1 | 1 | 1 | 1 | 3 | 2 | 2 | 2 | 2 | 2 | 5 | 3 | 2 | 2 | 3 | 2 | 1 | 2 | 2 | 1 | 1 | 2 | 2 | 2 | 2 | 3 | 3 | 3 | 0 | 1 |   |   | 0 | 2 | 1 | 1 | 1 | 2 | 1 | 1 | 3 | 2 | 1 | 1 | 7 | 2 | 1 | 2 | 1 | 3 | 1 | 2 | 1 | 2 | 4 | 1 | 1 | 2 | 1 | 1 | 2 | 2 | 1 | 1 | 2 | 2 | 1 | 1 |   |   |   | 2 | 1 | 3 | 1 | 2 | 2 | 2 | 2 | 1 | 2 | 7 | 1 | 3 | 2 | 2 | 1 | 1 | 3 | 2 | 1 | 2 | 3 |   |   |   |   |   |   |   |   |
| Query Sequence Evolutionary Trace | 6 | 6 | 3 | 5 | 7 | 9 | 8 | 2 |   |   | 7 | 1 | 0 | 5 | 1 | 8 | 6 | 2 | 1 | 7 | 4 | 4 | 2 | 5 | 2 | 5 | 5 | 3 | 3 | 4 | 1 | 6 | 4 | 5 | 1 | 0 | 6 | 3 | 7 | 9 | 1 | 9 | 4 | 7 | 5 | 6 | 6 | 9 | 2 | 1 | 0 | 8 | 7 | 8 | 1 | 0 | 4 | 8 | 7 |   | 6 | 7 | 7 | 7 | 3 | 2 | 3 | 6 | 9 | 3 | 5 | 8 | 3 | 2 | 9 | 9 | 1 | 6 | 8 | 5 | 0 | 8 | 5 | 2 | 0 | 8 | 7 | 5 | 7 | 8 |   |   | 9 | 8 | 6 | 5 | 5 | 5 | 2 | 3 | 2 | 6 | 5 | 1 | 8 | 8 | 5 | 3 | 1 | 0 | 3 | 3 | 7 | 8 | 1 | 0 | 9 | 9 | 3 | 9 | 1 | 0 | 6 | 5 | 7 | 6 | 4 | 5 |   |   |   | 4 | 4 | 8 | 8 | 7 | 1 | 0 | 4 | 3 | 3 | 8 | 9 | 6 | 6 | 3 | 7 | 6 | 8 | 3 | 7 | 1 | 0 |   |   |   |   |   |   |   |   |
|   |
| Query Predicted Secondary Structure | C | C | H | H | H | H | H | H | - | - | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | E | E | C | H | H | H | H | H | H | C | C | C | C | C | C | C | C | - | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | H | - | - | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | - | - | - | H | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | - | - | - | - | - | - | - | - |
| Query Sequence | S | V | Y | D | A | A | A | Q | - | - | L | T | A | D | V | K | K | D | L | R | D | S | W | K | V | I | G | S | D | K | K | G | N | G | V | A | L | M | T | T | L | F | A | D | N | Q | E | T | I | G | Y | F | K | R | L | G | N | V | S | - | Q | G | M | A | N | D | K | L | R | G | H | S | I | T | L | M | Y | A | L | Q | N | F | I | D | Q | L | D | N | P | D | - | - | D | L | V | C | V | V | E | K | F | A | V | N | H | I | T | R | K | I | S | A | A | E | F | G | K | I | N | G | P | I | K | K | V | L | A | S | - | - | - | K | N | F | G | D | K | Y | A | N | A | W | A | K | L | V | A | V | V | Q | A | A | L | - | - | - | - | - | - | - | - |
| Match Quality |   |   |   |   |   |   |   |   |   |   | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | - | + |   | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |   |   | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | - | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |   |   |   | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + | + |   |   |   |   |   |   |   |   |
| Alignment Accuracy |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| d2gdm__ Sequence | - | - | - | - | - | - | - | - | G | A | L | T | E | S | Q | A | A | L | V | K | S | S | W | E | E | F | N | A | N | I | P | K | H | T | H | R | F | F | I | L | V | L | E | I | A | P | A | A | K | D | L | F | S | F | L | K | G | T | S | E | V | P | Q | N | N | P | E | L | Q | A | H | A | G | K | V | F | K | L | V | Y | E | A | A | I | Q | L | E | V | T | G | V | V | V | T | D | A | T | L | K | N | L | G | S | V | H | V | S | K | G | V | A | D | A | H | F | P | V | V | K | E | A | I | L | K | T | I | K | E | V | V | G | A | K | W | S | E | E | L | N | S | A | W | T | I | A | Y | D | E | L | A | I | V | I | K | K | E | M | D | D | A | A |
| d2gdm__ Predicted Secondary Structure | - | - | - | - | - | - | - | - | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C |
| d2gdm__ Known Secondary Structure | - | - | - | - | - | - | - | - | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | G | G | G | G | G | G | T | T | T | T | T | T | T | T | T | T | T | T | T | T | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | C | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | C | C | C | G | G | G | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | G | G | G | C | C | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | H | C |
|   |
| Template Functional Sites |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | f |   |   | f | f | f | f |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | f |   |   | f | f |   |   | f | f |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | f |   |   | f | f |   |   | f |   | f |   |   |   | f | f |   |   | f |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | f |   |   | f | f |   |   | f |   |   |   |   |   |   |   |   |
| Model Pockets/Cavities/Clefts |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | 1 |   |   | 1 |   |   |   |   |   |   | 1 |   |   | 1 | 1 |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | 1 | 1 |   | 1 | 1 |   |   | 1 | 1 |   | 2 | 2 |   |   |   |   |   |   |   |   |   |   | 2 |   | 2 |   | 2 | 2 |   |   | 1 |   |   | 1 | 1 |   |   | 1 |   | 1 |   |   |   |   | 1 |   |   | 1 |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | 1 |   |   | 1 | 1 |   |   | 1 |   |   |   |   |   |   |   |   |
| Consensus Function |
1 | 1 | 0 | 1 | 1 | 2 | 2 | 0 |   |   | 3 | 1 | 1 | 1 | 0 | 3 | 1 | 0 | 0 | 2 | 1 | 1 | 2 | 1 | 0 | 2 | 2 | 1 | 1 | 1 | 0 | 1 | 1 | 3 | 1 | 0 | 2 | 3 | 2 | 2 | 4 | 4 | 1 | 2 | 1 | 1 | 1 | 7 | 0 | 0 | 5 | 9 | 3 | 3 | 0 | 1 | 1 | 2 | 2 |   | 1 | 2 | 2 | 2 | 1 | 0 | 1 | 2 | 3 | 1 | 8 | 4 | 1 | 4 | 6 | 3 | 0 | 7 | 6 | 1 | 1 | 3 | 1 | 0 | 0 | 3 | 4 | 2 | 1 | 2 |   |   | 3 | 3 | 3 | 1 | 3 | 2 | 0 | 1 | 4 | 2 | 2 | 4 | 8 | 2 | 1 | 4 | 0 | 3 | 1 | 1 | 2 | 3 | 7 | 0 | 2 | 6 | 1 | 3 | 0 | 1 | 1 | 1 | 3 | 3 | 3 | 1 |   |   |   | 1 | 1 | 4 | 2 | 2 | 0 | 0 | 1 | 1 | 2 | 3 | 2 | 4 | 2 | 4 | 3 | 2 | 7 | 4 | 2 | 1 | 6 |   |   |   |   |   |   |   |   |
| Template Index |
  |   |   |   |   |   |   |   | . | . | . | . | : | . | . | . | . | 10 | . | . | . | . | : | . | . | . | . | 20 | . | . | . | . | : | . | . | . | . | 30 | . | . | . | . | : | . | . | . | . | 40 | . | . | . | . | : | . | . | . | . | 50 | . | . | . | . | : | . | . | . | . | 60 | . | . | . | . | : | . | . | . | . | 70 | . | . | . | . | : | . | . | . | . | 80 | . | . | . | . | : | . | . | . | . | 90 | . | . | . | . | : | . | . | . | . | 100 | . | . | . | . | : | . | . | . | . | 110 | . | . | . | . | : | . | . | . | . | 120 | . | . | . | . | : | . | . | . | . | 130 | . | . | . | . | : | . | . | . | . | 140 | . | . | . | . | : | . | . | . | . | 150 | . | . |