3d2GO Protein Function Prediction Server

Full Details

Full topology search (3D-BLAST)

Full topology search (MAMMOTH)

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JS Cluster Site Search

Sequence Methods

GO	Description	Minimum E-value	Number of hits	Top PDB hit
GO:0003824	catalytic activity	2e-50	14	3LZT
GO:0003796	lysozyme activity	2e-50	3	3LZT
GO:0016787	hydrolase activity	2e-50	16	3LZT
GO:0019835	cytolysis	2e-50	3	3LZT
GO:0042742	defense response to bacterium	2e-50	5	3LZT
GO:0005576	extracellular region	2e-50	8	3LZT
GO:0008152	metabolic process	2e-50	9	3LZT
GO:0016998	cell wall catabolic process	2e-50	3	3LZT
GO:0016798	hydrolase activity, acting on glycosyl bonds	2e-50	3	3LZT
GO:0007267	cell-cell signaling	1e-34	1	1B9O
GO:0007165	signal transduction	1e-34	4	1B9O
GO:0006917	induction of apoptosis	1e-34	1	1B9O
GO:0005989	lactose biosynthetic process	1e-34	1	1B9O
GO:0004461	lactose synthase activity	1e-34	1	1B9O
GO:0005509	calcium ion binding	1e-34	6	1B9O
GO:0005615	extracellular space	1e-34	1	1B9O
GO:0016829	lyase activity	3e-09	4	1QSA
GO:0042597	periplasmic space	3e-09	4	1QSA
GO:0007047	cell wall organization	3e-09	2	1QSA
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	3e-09	2	1QSA
GO:0016837	carbon-oxygen lyase activity, acting on polysaccharides	3e-09	2	1QSA

GO	Description	Max -ln(E-value)	Number of hits	Top PDB hit
GO:0007267	cell-cell signaling	17.49	1	1B9O
GO:0042742	defense response to bacterium	17.49	3	1B9O
GO:0005989	lactose biosynthetic process	17.49	1	1B9O
GO:0007165	signal transduction	17.49	2	1B9O
GO:0005576	extracellular region	17.49	3	1B9O
GO:0004461	lactose synthase activity	17.49	1	1B9O
GO:0006917	induction of apoptosis	17.49	1	1B9O
GO:0005509	calcium ion binding	17.49	1	1B9O
GO:0005615	extracellular space	17.49	1	1B9O
GO:0016998	cell wall catabolic process	15.62	3	1IIZ
GO:0003824	catalytic activity	15.62	2	1IIZ
GO:0003796	lysozyme activity	15.62	2	1IIZ
GO:0016787	hydrolase activity	15.62	6	1IIZ
GO:0016798	hydrolase activity, acting on glycosyl bonds	15.62	3	1IIZ
GO:0019835	cytolysis	15.62	2	1IIZ
GO:0008152	metabolic process	15.62	3	1IIZ
GO:0016829	lyase activity	8.811	5	1QSA
GO:0042597	periplasmic space	8.811	2	1QSA
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	8.811	2	1QSA
GO:0007047	cell wall organization	8.811	3	1QSA
GO:0016837	carbon-oxygen lyase activity, acting on polysaccharides	8.811	3	1QSA

GO	Description	Minimum E-value	Number of hits	Top PDB hit
GO:0008152	metabolic process	0.000285	16	2Z2F
GO:0042742	defense response to bacterium	0.000285	7	2Z2F
GO:0005576	extracellular region	0.000285	17	2Z2F
GO:0003824	catalytic activity	0.000285	19	2Z2F
GO:0003796	lysozyme activity	0.000285	9	2Z2F
GO:0019835	cytolysis	0.000285	7	2Z2F
GO:0016787	hydrolase activity	0.000285	19	2Z2F
GO:0016998	cell wall catabolic process	0.000285	9	2Z2F
GO:0016798	hydrolase activity, acting on glycosyl bonds	0.000285	11	2Z2F
GO:0007586	digestion	0.000285	1	2Z2F
GO:0005515	protein binding	0.000424	8	2NWD
GO:0006954	inflammatory response	0.000424	1	2NWD
GO:0005615	extracellular space	0.000424	3	2NWD
GO:0006355	regulation of transcription, DNA-dependent	0.000955	2	2HYT
GO:0003677	DNA binding	0.000955	4	2HYT
GO:0006350	transcription	0.000955	2	2HYT
GO:0003700	transcription factor activity	0.000955	1	2HYT
GO:0045449	regulation of transcription	0.000955	1	2HYT
GO:0016740	transferase activity	0.00114	3	3CUZ
GO:0005737	cytoplasm	0.00114	11	3CUZ
GO:0006097	glyoxylate cycle	0.00114	2	3CUZ

GO	Description	Minimum E-value	Number of hits	Top PDB hit
GO:0003796	lysozyme activity	7.16e-05	5	2GV0
GO:0005576	extracellular region	7.16e-05	16	2GV0
GO:0042742	defense response to bacterium	7.16e-05	4	2GV0
GO:0016798	hydrolase activity, acting on glycosyl bonds	7.16e-05	9	2GV0
GO:0019835	cytolysis	7.16e-05	3	2GV0
GO:0008152	metabolic process	7.16e-05	20	2GV0
GO:0016787	hydrolase activity	7.16e-05	19	2GV0
GO:0003824	catalytic activity	7.16e-05	19	2GV0
GO:0016998	cell wall catabolic process	7.16e-05	5	2GV0
GO:0016021	integral to membrane	0.000517	5	1DL2
GO:0005509	calcium ion binding	0.000517	7	1DL2
GO:0006487	protein amino acid N-linked glycosylation	0.000517	1	1DL2
GO:0030433	ER-associated protein catabolic process	0.000517	1	1DL2
GO:0016020	membrane	0.000517	13	1DL2
GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	0.000517	1	1DL2
GO:0005783	endoplasmic reticulum	0.000517	2	1DL2
GO:0005789	endoplasmic reticulum membrane	0.000517	1	1DL2
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	0.000517	7	1UPS
GO:0005975	carbohydrate metabolic process	0.000517	12	1UPS
GO:0030145	manganese ion binding	0.00093	3	2LTN
GO:0005529	sugar binding	0.00093	3	2LTN

GO	Description	Minimum E-value	Number of hits	Top PDB hit
GO:0003824	catalytic activity	0.00038	33	2VB1
GO:0003796	lysozyme activity	0.00038	9	2VB1
GO:0005576	extracellular region	0.00038	24	2VB1
GO:0019835	cytolysis	0.00038	7	2VB1
GO:0042742	defense response to bacterium	0.00038	8	2VB1
GO:0016798	hydrolase activity, acting on glycosyl bonds	0.00038	12	2VB1
GO:0016787	hydrolase activity	0.00038	24	2VB1
GO:0008152	metabolic process	0.00038	25	2VB1
GO:0016998	cell wall catabolic process	0.00038	9	2VB1
GO:0005509	calcium ion binding	0.00038	7	1HFX
GO:0004461	lactose synthase activity	0.00038	3	1HFX
GO:0005989	lactose biosynthetic process	0.00038	3	1HFX
GO:0007586	digestion	0.000425	1	2Z2F
GO:0005515	protein binding	0.000492	22	2NWD
GO:0005615	extracellular space	0.000492	4	2NWD
GO:0006954	inflammatory response	0.000492	1	2NWD
GO:0005886	plasma membrane	0.000985	9	1ZXK
GO:0016021	integral to membrane	0.000985	6	1ZXK
GO:0007156	homophilic cell adhesion	0.000985	1	1ZXK
GO:0016020	membrane	0.000985	13	1ZXK
GO:0007155	cell adhesion	0.000985	2	1ZXK

GO	Description	Confidence
GO:0003796	lysozyme activity	1
GO:0005975	carbohydrate metabolism	1
GO:0009607	response to biotic stimulus	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	1
GO:0005989	lactose biosynthesis	1
GO:0016998	cell wall catabolism	1
GO:0050789	regulation of biological process	1
GO:0019835	cytolysis	1
GO:0005576	extracellular region	1
GO:0006740	NADPH regeneration	1
GO:0009452	RNA capping	1
GO:0005488	binding	0.933
GO:0043231	intracellular membrane-bound organelle	0.891
GO:0009056	catabolism	0.88
GO:0003824	catalytic activity	0.865
GO:0008152	metabolism	0.849
GO:0016787	hydrolase activity	0.844
GO:0017076	purine nucleotide binding	0.831
GO:0051186	cofactor metabolism	0.827
GO:0044270	nitrogen compound catabolism	0.818
GO:0009051	pentose-phosphate shunt, oxidative branch	0.816

© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley