Over the past few years we have collected information on the preparation and
characterisation of HEAVY-ATOM derivatives of protein crystals. This information
has been assembled in the form of a DATABANK
(called HAD).
In addition to the experimental information this databank also contains
information resulting from an analysis of the binding of these heavy-atoms
with proteins in the crystal environment. In summary, the databank contains the following
information:
This databank will be of interest, not only to protein crystallographers but to
anyone interested in the interaction of heavy-atoms with proteins.
We would like to thank the many Crystallographers who kindly
provided information which was not available in the literature.
Please send all comments/queries to Suhail A. Islam
David Carvin, Suhail A Islam, Michael JE Sternberg and Thomas L Blundell
David Carvin, Suhail A Islam, Michael JE Sternberg and Thomas L Blundell
REFERENCES
Establishment of a Heavy-Atom Databank for Protein Structures
Isomorphous Replacement and Anomalous Scattering.
Proceedings of CCP4 Study Weekend - 25-26 January 1991
Science and Engineering Research Council, Daresbury Laboratory
HAD, A Databank of Heavy-Atom binding sites in protein crystals: A resource for use
in multiple isomorphous replacement and anomalous scattering.
Acta. Cryst., Sect. D-Biological Crystallography. Nov 1 1998; 54 Part 6 Special Iss. S1: 1199-1206